PARENTERAL PHARMACEUTICAL FORMULATION IN SUSPENSION, HAVING SUSTAINED RELEASE, IN LOW AND ULTRALOW DOSAGE, IN HORMONAL THERAPY IN THE CLIMACTERIC SYNDROME

Title:

PARENTERAL PHARMACEUTICAL FORMULATION IN SUSPENSION, HAVING SUSTAINED RELEASE, IN LOW AND ULTRALOW DOSAGE, IN HORMONAL THERAPY IN THE CLIMACTERIC SYNDROME

Document Type and Number:

WIPO Patent Application WO/2011/074931

Kind Code:

A3

Abstract:

Parenteral pharmaceutical formulation or composition, in suspension, having sustained release, containing suspended particles of estradiol and progesterone for hormonal replacement in female mammals in low and ultralow dosage; the formulation consists of an injectable suspension comprising particles of estradiol, particles of progesterone, a surfactant agent, an isosmotic agent, a thickening agent, and one or more preservation agents, wherein the estradiol is in particles having a size between 1 and 100 microns and the progesterone is in particles having a size between 1 and 100 microns, for application thereof in parenteral, intramuscular, subcutaneous or intradermal pharmaceutical form.

Inventors:

ANGELES URIBE JUAN (MX)
SAVOIR VILBOEUF JOHN CLAUDE (MX)

Application Number:

PCT/MX2010/000154

Publication Date:

September 22, 2011

Filing Date:

December 14, 2010

Export Citation:

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Assignee:

TECHSPHERE S A DE C V (MX)
ANGELES URIBE JUAN (MX)
SAVOIR VILBOEUF JOHN CLAUDE (MX)

International Classes:

A61K31/565; A61K9/16; A61K31/57; A61P5/30; A61P5/34

Domestic Patent References:

WO2004110408A2

2004-12-23

Foreign References:

US6287693B1	2001-09-11
US6077531A	2000-06-20

Other References: