Title:
PARTICLES AND PHARMACEUTICAL PREPARATION
Document Type and Number:
WIPO Patent Application WO/2017/119506
Kind Code:
A1
Abstract:
To provide active-ingredient-containing particles having higher absorption of the active ingredient into a body. Particles including a first fraction containing an active ingredient and a second fraction containing a surfactant, wherein the aggregability index X of the particles represented by formula (1) is 30 or less. Formula (1): X = (S1/Sr1)/(SO/Sr0) [In formula (1): S1 represents the scattering intensity when the scattering vector q in a scattering profile obtained by small-angle X-ray scattering in the particles is 0.2 [nm-1]; Sr1 represents the maximum value of the scattering intensity in the scattering profile obtained by small-angle X-ray scattering in the particles; S0 represents the scattering intensity when the scattering vector q in a scattering profile obtained by small-angle X-ray scattering in the surfactant is 0.2 [nm-1]; and Sr0 represents the maximum value of the scattering intensity in the scattering profile obtained by small-angle X-ray scattering in the surfactant.]
Inventors:
KAWAMURA DAICHI (JP)
MATSUMOTO IZUMI (JP)
AKAMINE TAKAYUKI (JP)
TONE SAORI (JP)
ITOU KAZUSHI (JP)
ABE YOSHIKO (JP)
MATSUMOTO IZUMI (JP)
AKAMINE TAKAYUKI (JP)
TONE SAORI (JP)
ITOU KAZUSHI (JP)
ABE YOSHIKO (JP)
Application Number:
PCT/JP2017/000333
Publication Date:
July 13, 2017
Filing Date:
January 06, 2017
Export Citation:
Assignee:
SEKISUI CHEMICAL CO LTD (JP)
International Classes:
A61K9/14; A61K8/02
Domestic Patent References:
| WO2009057808A1 | 2009-05-07 | |||
| WO2009139506A1 | 2009-11-19 | |||
| WO2016098857A1 | 2016-06-23 | |||
| WO2016043323A1 | 2016-03-24 | |||
| WO2017002865A1 | 2017-01-05 | |||
| WO2016047757A1 | 2016-03-31 |
Foreign References:
| JP2014172840A | 2014-09-22 | |||
| JP2016179962A | 2016-10-13 |
Attorney, Agent or Firm:
MIYAZAKI & METSUGI (JP)
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