Title:
PATCH AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2023/022097
Kind Code:
A1
Abstract:
Provided is a patch having an adhesive layer, the patch being characterized in that the adhesive layer contains (a) a drug, (b) a thermoplastic elastomer, and (c) a non-volatile hydrocarbon oil having a kinematic viscosity at 40°C of 70 mm2/s or less, wherein the drug (a) has a structure having (i) an amino group which may have a substituent, and (ii) at least one functional group which may have a substituent and is selected from an ester group, an amide group, an ether group, a ketone group, a thioether group, and an amino group different from the above (i), the amino group of the above (i) and the at least one functional group of the above (ii) are bonded to each other via a C1-3 hydrocarbon chain, the number of hydroxyl groups in the drug (a) is 4 or less per one molecule, and the content of the non-volatile hydrocarbon oil (c) is 230 parts by mass or less with respect to 100 parts by mass of the thermoplastic elastomer (b). Also provided is a patch having an adhesive layer, the patch being characterized in that the adhesive layer contains (a) a drug, (b) a mixture of a styrene/isoprene/styrene block copolymer and a styrene/isoprene block copolymer, and (c) a non-volatile hydrocarbon oil having a kinematic viscosity at 40°C of 60 mm2/s or less, wherein the drug (a) has a structure having (i) an amino group which may have a substituent, and (ii) at least one functional group which may have a substituent and is selected from a hydroxyl group, an ester group, an amide group, an ether group, a ketone group, thioether group, and an amino group different from the above (i), the amino group of the above (i) and the at least one functional group of the above (ii) are bonded to each other via a C1-5 hydrocarbon chain, the number of hydroxyl groups in the drug (a) is 4 or less per one molecule, and the content of the styrene/isoprene block copolymer in the mixture (b) is 20 mass% or more.
Inventors:
MIZUTANI MASAYA (JP)
OGINO HIROYUKI (JP)
GOTO MASAOKI (JP)
OGINO HIROYUKI (JP)
GOTO MASAOKI (JP)
Application Number:
PCT/JP2022/030654
Publication Date:
February 23, 2023
Filing Date:
August 10, 2022
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
A61K47/30; A61K9/70; A61K47/06; A61K47/32
Domestic Patent References:
| WO2010103844A1 | 2010-09-16 | |||
| WO2013027681A1 | 2013-02-28 | |||
| WO2013133388A1 | 2013-09-12 | |||
| WO2014200072A1 | 2014-12-18 | |||
| WO2008032678A1 | 2008-03-20 |
Foreign References:
| JP2010053095A | 2010-03-11 | |||
| JP2017154989A | 2017-09-07 | |||
| JP2016003196A | 2016-01-12 |
Attorney, Agent or Firm:
ITOH, Tadashige et al. (JP)
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