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Title:
PATENTIFLORIN A ANALOGS AS ANTIVIRAL AGENTS
Document Type and Number:
WIPO Patent Application WO/2021/037077
Kind Code:
A1
Abstract:
Patentiflorin A analogs that are useful as antivirals, such as anti-HIV, anti-coronaviral, anti-Ebola viral, and anti-influenza viral agents and methods of use thereof.

Inventors:
ZHANG HONGJIE (CN)
LI WANFEI (CN)
TSANG NGA YI (CN)
Application Number:
PCT/CN2020/111463
Publication Date:
March 04, 2021
Filing Date:
August 26, 2020
Export Citation:
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Assignee:
UNIV HONG KONG BAPTIST UNIV (CN)
International Classes:
A61K31/34; A61K31/7028; A61P31/00; C07D407/02; C07H15/252; C07H17/04
Foreign References:
US20140357584A12014-12-04
US4486445A1984-12-04
Other References:
ZHANG HONG-JIE, RUMSCHLAG-BOOMS EMILY, GUAN YI-FU, WANG DONG-YING, LIU KANG-LUN, LI WAN-FEI, NGUYEN VAN H., CUONG NGUYEN M., SOEJA: "Potent Inhibitor of Drug-Resistant HIV-1 Strains Identified from the Medicinal Plant Justicia gendarussa", JOURNAL OF NATURAL PRODUCTS, AMERICAN CHEMICAL SOCIETY, US, vol. 80, no. 6, 23 June 2017 (2017-06-23), US, pages 1798 - 1807, XP055785691, ISSN: 0163-3864, DOI: 10.1021/acs.jnatprod.7b00004
ZHANG HONG-JIE; RUMSCHLAG-BOOMS EMILY; GUAN YI-FU; LIU KANG-LUN; WANG DONG-YING; LI WAN-FEI; NGUYEN VAN HUNG; CUONG NGUYEN MANH; S: "Anti-HIV diphyllin glycosides fromJusticia gendarussa", PHYTOCHEMISTRY, ELSEVIER, AMSTERDAM , NL, vol. 136, 1 January 1900 (1900-01-01), Amsterdam , NL, pages 94 - 100, XP029934524, ISSN: 0031-9422, DOI: 10.1016/j.phytochem.2017.01.005
Attorney, Agent or Firm:
BEIJING PAT SF INTELLECTUAL PROPERTY AGENCY CO. LTD (CN)
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