PEG BASED ANTI-CD47/ANIT-PD-L1 BISPECIFIC ANTIBODY-DRUG CONJUGATE

Title:

PEG BASED ANTI-CD47/ANIT-PD-L1 BISPECIFIC ANTIBODY-DRUG CONJUGATE

Document Type and Number:

WIPO Patent Application WO/2024/022384

Kind Code:

A1

Abstract:

An antibody-drug conjugate (ADC) especially PEG based bispecific antibody-drug conjugate (P-BsADC) comprises an antigen binding domain bonding to CD47 and PD-L1. A method for the preparation of the P-BsADC, a composition comprising the P-BsADC, and the use thereof in treating diseases.

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Inventors:

LIU SHUMIN (CN)
LYU WEIDONG (CN)
YIN SHUQIANG (CN)
WEN YU (CN)
WU DECHUN (CN)

Application Number:

PCT/CN2023/109315

Publication Date:

February 01, 2024

Filing Date:

July 26, 2023

Export Citation:

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Assignee:

SHENZHEN ENDURING BIOTECH LTD (CN)

International Classes:

A61K47/68; A61K47/00; A61K47/10; A61K47/36; A61P35/00; C07K16/46; C07K19/00

Foreign References:

CN114502200A	2022-05-13
CN113321734A	2021-08-31
CN111518214A	2020-08-11
CN113692413A	2021-11-23
CN113784728A	2021-12-10
CN114249830A	2022-03-29
US20200270345A1	2020-08-27

Attorney, Agent or Firm:

LIU , SHEN & ASSOCIATES (CN)

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