Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PENTADIENAMIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2008/007780
Kind Code:
A1
Abstract:
Disclosed is a pentadienamide derivative represented by the formula (I) or a pharmaceutically acceptable salt thereof or the like. (I) wherein R1 represents a substituted or unsubstituted aryl or a substituted or unsubstituted aromatic heterocyclic group; R2 represents a substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group, a substituted or unsubstituted alicyclic heterocyclic group or the like; R3 represents a hydrogen atom or, together with R4 and a nitrogen atom adjacent to R3, forms a substituted or unsubstituted heterocyclic group; R4 represents a substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group, a substituted or unsubstituted alicyclic heterocyclic group or the like, or, together with R3 and a nitrogen atom adjacent to R4, forms a substituted or unsubstituted heterocyclic group; and R5, R6 and R7 independently represent a hydrogen atom or a methyl.

More Like This:
JPS5817749[Title of the Invention] A manufacturing method of 2 and 2-diaryl 4-(4'-Ally Lu 4'-hydroxy piperidino) butyl amide
JP5779142Synthesis of functional and non-functional olefins by cross-metathesis and ring-closing metathesis
JP2015166370NOVEL COMPOUND ADVANTAGEOUS IN TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASE AND DISORDER
Inventors:
NAKASATO YOSHISUKE
SAKU OSAMU
ATSUMI ERI
SUGIMOTO YOSHIYUKI
ISHIDA HIROSHI
Application Number:
PCT/JP2007/064007
Publication Date:
January 17, 2008
Filing Date:
July 13, 2007
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KYOWA HAKKO KOGYO KK (JP)
NAKASATO YOSHISUKE
SAKU OSAMU
ATSUMI ERI
SUGIMOTO YOSHIYUKI
ISHIDA HIROSHI
International Classes:
C07C233/11; A61K31/167; A61K31/18; A61K31/277; A61K31/416; A61K31/4184; A61K31/4245; A61K31/428; A61K31/433; A61K31/44; A61K31/4406; A61K31/4409; A61K31/4427; A61K31/443; A61K31/47; A61K31/4709; A61K31/472; A61K31/4725; A61K31/496; A61K31/506; A61K31/536; A61K31/538; A61K31/54; A61P25/00; A61P43/00; C07C233/27; C07C233/30; C07C255/58; C07C307/02; C07C311/46; C07C317/40; C07D209/08; C07D213/40; C07D213/64; C07D213/74; C07D213/75; C07D215/38; C07D217/02; C07D217/24; C07D217/26; C07D231/56; C07D235/12; C07D265/18; C07D265/36; C07D271/06; C07D277/62; C07D277/82; C07D279/12; C07D285/135; C07D295/18; C07D311/04; C07D319/18; C07D401/06; C07D401/12; C07D405/12; C07D409/12
Domestic Patent References:
WO2005044786A12005-05-19
WO2003049702A22003-06-19
WO2005044802A22005-05-19
WO2004078744A22004-09-16
WO2005016915A12005-02-24
WO2006058338A22006-06-01
Foreign References:
JPS6431766A1989-02-02
JPH05230069A1993-09-07
US3244701A1966-04-05
JP2005518371A2005-06-23
JP2005517737A2005-06-16
US4788206A1988-11-29
JPH07316144A1995-12-05
EP0124791A11984-11-14
Other References:
GUTHRIE R.W. ET AL.: "Pentadienyl Carboxamide Derivatives as Antagonists of Platelet-Activating Factor", J. MED. CHEM., vol. 32, no. 8, 1989, pages 1820 - 1835, XP002037072
COLWELL W.T. ET AL.: "5,5-Diarylpenta-2,4-dienoic Acid Amides as Potential Antimalarial Agents", J. MED. CHEM., vol. 11, 1968, pages 749 - 752, XP003020482
LANGE J.H. ET AL.: "5,5-Diarylpenta-2,4-dienoic Acid Amides as Potential Antimalarial Agents. II", J. MED. CHEM., vol. 12, 1969, pages 946 - 947, XP003020483
ARPAD ZSALLASI: "Piperine: researchers discover new flavor in an ancient spice", TRENDS PHARMACOL. SCI., vol. 26, no. 9, 2005, pages 437 - 439, XP005044762
GARLE M.J. ET AL.: "Stimulation of Dichlorofluorescin Oxidation by Capsaicin and Analogues in RAW 264 Monocyte/Vanilloid Receptor", BIOCHEMICAL PHARMACOLOGY, vol. 59, no. 5, 2000, pages 563 - 572, XP003020484
APPENDINO G. ET AL.: "The Taming of Capsaicin. Reversal of the Vanilloid Activity of N-Acylvanillamines by Aromatic Iodination", J. MED. CHEM., vol. 48, no. 14, 2005, pages 4663 - 4669, XP003020485
NATURE, vol. 389, 1997, pages 816
NATURE, vol. 405, 2000, pages 183
PHARMACOLOGICAL REVIEWS, vol. 51, 1999, pages 159
LIFE SCIENCES, vol. 51, 1992, pages 1777
JOURNAL OF UROLOGY, vol. 158, 1997, pages 2087
THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 304, 2003, pages 56
THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 306, 2003, pages 387
JOURNAL OF MEDICINAL CHEMISTRY, vol. 12, 1969, pages 946
JOURNAL OF MEDICINAL CHEMISTRY, vol. 11, 1968, pages 749
"Protective Groups in Organic Synthesis", 1999, JOHN WILEY & SONS INC.
"Synthesis of Organic Compounds VI, Organic Syntheses Using Metals", 2005, article "The Experimental Chemical Course 18 (Jikken Kagaku Koza 18)", pages: 97
"Synthesis of Organic Compounds I, Hydrocarbons/Halides", 2005, article "The Experimental Chemical Course 13 (Jikken Kagaku Koza 13)", pages: 283
R. C. LAROCK, COMPREHENSIVE ORGANIC TRANSFORMATIONS, 1989
THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 267, 1993, pages 728 - 733
KRUGER ET AL., PAIN, vol. 64, 1996, pages 37 - 57
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, vol. 20, 1980, pages 441 - 462
CHEMICAL REVIEWS, vol. 102, 2002, pages 29 - 60
CHEMICAL & PHARMACEUTICAL BULLTIN, vol. 43, 1995, pages 493 - 498
JOURNAL OF ORGANIC CHEMISTRY, vol. 51, 1986, pages 3143 - 3147
JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 23, 1986, pages 1253 - 1255
BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 10, 2000, pages 1459 - 1462
JOURNAL OF MEDICINAL CHEMISTRY, vol. 11, 1968, pages 700 - 703
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: MICROWAVE INDUCTION HEATING DEVICE

Next Patent: METHOD FOR PRODUCING CIRCULARLY POLARIZED LIGHT ISOLATION SHEET, AND APPARATUS FOR COATING FILM FORM...