PEPTIDE ANTAGONIST OF LL-37 - UNIV INDIANA RES & TECH CORP

Title:

PEPTIDE ANTAGONIST OF LL-37

Document Type and Number:

WIPO Patent Application WO/2015/183683

Kind Code:

A3

Abstract:

This disclosure is related to the peptide antagonist of LL-37, an antimicrobial peptide that has multiple functions in both innate and adaptive immune response. Specifically, the identified peptide antagonists of LL-37 provide inhibition to detrimental autoimmune inflammatory response, whereas at the same time retain LL-37's antibacterial activity.

Inventors:

KAO C CHENG (US)
SINGH DIVYENDU (US)
SAN MATEO LANI ROSE (US)

Application Number:

PCT/US2015/031928

Publication Date:

January 21, 2016

Filing Date:

May 21, 2015

Export Citation:

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Assignee:

UNIV INDIANA RES & TECH CORP (US)
JANSSEN BIOTECH INC (US)

International Classes:

C07K16/00; A01N37/18; C12P21/08

Foreign References:

US20070065908A1	2007-03-22
US20130287839A1	2013-10-31
US20120315290A1	2012-12-13
US20140017787A1	2014-01-16

Attorney, Agent or Firm:

HOU, Yonghao (300 N. Meridian StreetIndianapolis, Indiana, US)

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