Title:
PEPTIDE CATALYZING LUMINESCENCE REACTION
Document Type and Number:
WIPO Patent Application WO/2023/038157
Kind Code:
A1
Abstract:
The present invention provides: a short peptide catalyzing the luminescence reaction of luciferin; a production method of the peptide; a bioluminescence analysis kit containing the peptide; use of the peptide as a bioluminescence probe; a polynucleotide encoding the peptide; an expression vector containing the polynucleotide; a cell having the expression vector transferred thereinto, etc.
Inventors:
NISHIHARA RYO (JP)
KURITA RYOJI (JP)
KURITA RYOJI (JP)
Application Number:
PCT/JP2022/034659
Publication Date:
March 16, 2023
Filing Date:
September 12, 2022
Export Citation:
Assignee:
AIST (JP)
International Classes:
C07K7/08; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/02; C12N15/12; C12N15/53; C12N15/63; C12P21/00
Foreign References:
| JP2012130282A | 2012-07-12 | |||
| JP2018158896A | 2018-10-11 |
Other References:
VASSEL N, COX CD, NASEEM R, MORSE V, EVANS RT, POWER RL, BRANCALE A, WANN KT, CAMPBELL AK: "Enzymatic activity of albumin shown by coelenterazine chemiluminescence : Albumin catalysed coelenterazine chemiluminescence", LUMINESCENCE: THE JOURNAL OF BIOLOGICAL AND CHEMICAL LUMINESCENCE, JOHN WILEY & SONS LTD, GB, vol. 27, no. 3, 1 May 2012 (2012-05-01), GB , pages 234 - 241, XP055859048, ISSN: 1522-7235, DOI: 10.1002/bio.2357
NISHIHARA RYO, NIWA KAZUKI, TOMITA TATSUNOSUKE, KURITA RYOJI: "Coelenterazine Analogue with Human Serum Albumin-Specific Bioluminescence", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 31, no. 12, 16 December 2020 (2020-12-16), US , pages 2679 - 2684, XP055859050, ISSN: 1043-1802, DOI: 10.1021/acs.bioconjchem.0c00536
NISHIHARA RYO, NIWA KAZUKI, TOMITA TATSUNOSUKE, KURITA RYOJI: "Coelenterazine Analogue with Human Serum Albumin-Specific Bioluminescence", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 31, no. 12, 16 December 2020 (2020-12-16), US , pages 2679 - 2684, XP055859050, ISSN: 1043-1802, DOI: 10.1021/acs.bioconjchem.0c00536
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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