Title:
PEPTIDE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2000/004042
Kind Code:
A1
Abstract:
Peptide compounds represented by general formula (I) or salts thereof, which exhibit immunological enhancement effects, wherein R?1¿ and R?2¿ are each independently optionally substituted hydroxyl or optionally substituted amino; and X is C¿1?-C¿6? alkyl which may be substituted with -(CH¿2?)¿2?-COOH or the like.
Inventors:
SHINBARA NAOKI (JP)
NIWA SHINICHIRO (JP)
NIWA SHINICHIRO (JP)
Application Number:
PCT/JP1999/003820
Publication Date:
January 27, 2000
Filing Date:
July 15, 1999
Export Citation:
Assignee:
SUMITOMO ELECTRIC INDUSTRIES (JP)
SHINBARA NAOKI (JP)
NIWA SHINICHIRO (JP)
SHINBARA NAOKI (JP)
NIWA SHINICHIRO (JP)
International Classes:
C07K5/103; A61K38/00; (IPC1-7): C07K5/103; A61K38/03
Other References:
JOON YOUNG AHN ET AL: "Primary structures of two homologous subunits of PA28, a gamma-interferon-inducible protein activator of the 20S proteasome", FEBS, vol. 366, no. 1, 1995, pages 37 - 42, XP002926394
MA CHU-PING ET AL: "PA28, an Activator of the 20S proteasome, is Inactivated by Proteolytic Modification at Its Carboxyl Terminus", J. BIOL. CHEM., vol. 268, no. 30, 1993, pages 22514 - 22519, XP002926395
SHERWIN WILK ET AL: "Synthetic peptide-based activators of the proteasome", MOLECULAR BIOLOGY REPORTS, vol. 24, 1997, pages 119 - 124, XP002926605
MA CHU-PING ET AL: "PA28, an Activator of the 20S proteasome, is Inactivated by Proteolytic Modification at Its Carboxyl Terminus", J. BIOL. CHEM., vol. 268, no. 30, 1993, pages 22514 - 22519, XP002926395
SHERWIN WILK ET AL: "Synthetic peptide-based activators of the proteasome", MOLECULAR BIOLOGY REPORTS, vol. 24, 1997, pages 119 - 124, XP002926605
Attorney, Agent or Firm:
Imamura, Masazumi (Kyobashi 1-chome Chuo-ku Tokyo, JP)
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