Title:
PEPTIDE ENTITIES WITH ANTIMICROBIAL ACTIVITY AGAINST MULTI-DRUG RESISTANT PATHOGENS
Document Type and Number:
WIPO Patent Application WO/2022/105948
Kind Code:
A3
Abstract:
The present invention describes synthetic peptide-based compounds that are active against pathogenic microorganisms of a bacterial nature and which present as microorganisms multi-resistant to conventional antibiotics. The invention also describes combination therapies containing said peptides. Pharmaceutical compositions comprising the peptide-based compounds and combinations thereof are described, along with the uses thereof and treatment methods in which same can be used.
Inventors:
MONTERO-ALEJO VIVIAN (CU)
PERDOMO-MORALES ROLANDO (CU)
VÁZQUEZ-GONZÁLEZ AMANDA (CU)
GARAY-PEREZ HILDA ELISA (CU)
PERDOMO-MORALES ROLANDO (CU)
VÁZQUEZ-GONZÁLEZ AMANDA (CU)
GARAY-PEREZ HILDA ELISA (CU)
Application Number:
PCT/CU2021/050011
Publication Date:
October 20, 2022
Filing Date:
November 18, 2021
Export Citation:
Assignee:
CENTRO DE INVESTIG Y DESARROLLO DE MEDICAMENTOS CIDEM (CU)
International Classes:
C07K14/435; A61K38/17
Domestic Patent References:
| WO2018209127A1 | 2018-11-15 | |||
| WO1997008199A2 | 1997-03-06 |
Other References:
MONTERO-ALEJO VIVIAN ET AL: "Panusin represents a new family of [beta]-defensin-like peptides in invertebrates", DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, PERGAMON PRESS, US, vol. 67, 9 September 2016 (2016-09-09), pages 310 - 321, XP029827982, ISSN: 0145-305X, DOI: 10.1016/J.DCI.2016.09.002
NAGARAJAN KRISHNANAND ET AL: "Peptide Therapeutics Versus Superbugs: Highlight on Current Research and Advancements", INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, SPRINGER-VERLAG, DORDRECHT, NL, vol. 24, no. 1, 28 November 2017 (2017-11-28), pages 19 - 33, XP036448463, ISSN: 1573-3149, [retrieved on 20171128], DOI: 10.1007/S10989-017-9650-0
NAGARAJAN KRISHNANAND ET AL: "Peptide Therapeutics Versus Superbugs: Highlight on Current Research and Advancements", INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, SPRINGER-VERLAG, DORDRECHT, NL, vol. 24, no. 1, 28 November 2017 (2017-11-28), pages 19 - 33, XP036448463, ISSN: 1573-3149, [retrieved on 20171128], DOI: 10.1007/S10989-017-9650-0
Attorney, Agent or Firm:
BÁRZAGA-FERNÁNDEZ, Pedro Gilberto (CU)
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