Title:
PEPTIDE HAVING ANTI-HYPERTENSIVE ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2007/108554
Kind Code:
A1
Abstract:
The object is to provide an enzymatic collagen hydrolysate or a peptide which has an ACE (angiotensin converting enzyme)-inhibiting activity (i.e., an anti-hypertensive activity)/a blood vessel protection activity. Disclosed is a protease hydrolysate of a chicken or porcine collagen, which has an anti-hypertensive activity and/or a blood vessel protection activity, particularly a peptide which is a protease hydrolysate of a chicken or porcine collagen and has a molecular weight of 3000 or less. The protease hydrolysate of a chicken or porcine collagen or the peptide has an ACE-inhibiting activity and/or a blood vessel protection activity, and therefore is useful as a functional food having an anti-hypertensive activity and/or a blood vessel protection activity or the like.
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Inventors:
SAIGA AI (JP)
IWAI KOJI (JP)
TAKAHATA YOSHIHISA (JP)
IWAI KOJI (JP)
TAKAHATA YOSHIHISA (JP)
Application Number:
PCT/JP2007/056143
Publication Date:
September 27, 2007
Filing Date:
March 19, 2007
Export Citation:
Assignee:
NIPPON MEAT PACKERS (JP)
SAIGA AI (JP)
IWAI KOJI (JP)
TAKAHATA YOSHIHISA (JP)
SAIGA AI (JP)
IWAI KOJI (JP)
TAKAHATA YOSHIHISA (JP)
International Classes:
C07K14/78; A23J3/06; A23J3/34; A23L1/305; A61K35/32; A61K35/36; A61K38/00; A61K38/17; A61P9/12; A61P9/14; A61P43/00; C07K14/465; C07K14/47
Foreign References:
| JP2003284551A | 2003-10-07 |
Other References:
YOSHIWARA S. ET AL.: "Dobutsu Hone Collagen Yurai Angiotensin Henkan Koso Sogai Peptide", THE JAPANESE SOCIETY OF NUTRITION AND FOOD SCIENCE NISHINIHON SHIBU TAIKAI PROGRAM.KOEN YOSHISHU, vol. 2003, 2003, pages 34 + ABSTR. NO. A1-AM7, XP003017891
SAIGA A. ET AL.: "Angiotensin I-Converting Enzyme Inhibitory Peptides in a Hydrolyzed Chicken Breast Muscle Extract", J. AGRIC. FOOD CHEM., vol. 51, no. 6, 2003, pages 1741 - 1745, XP003017892
MARUYAMA S.: "Shokuhin Yurai Protease Sogai Seibun no Seirikassei", BIOSCIENCE & INDUSTRY, vol. 59, no. 8, 2001, pages 534 - 537, XP003017893
YAMADA R. ET AL.: "Kinosei Chikusanbutsu no Genjo to Kadai Shokuniku oyobi Chikusan Fukusanbutsu Yurai no Kinosei ni tsuite -Kagakuteki Data ni Motozuita Kinosei Sozai no Teian-", CHIKUSAN CONSULTANT, vol. 41, no. 8, 2005, pages 33 - 39, XP003017894
THE JAPANESE SOCIETY ZOOTECHNICAL SCIENCE ANNUAL MEETING ABSTRACTS, vol. 106TH, 20 March 2006 (2006-03-20), pages 163 + ABSTR. NO. XI31-19, XP003017895
SOGA A. ET AL.: "Buta Collagen peptide no Ketsuatsu Josho Yokusei Sayo", THE JAPANESE SOCIETY OF NUTRITION AND FOOD SCIENCE SOKAI KOEN YOSHISHU, vol. 60TH, 1 April 2006 (2006-04-01), pages 375 + ABSTR. NO. 3J-14A, XP003017896
SAIGA A. ET AL.: "Angiotensin I-Converting Enzyme Inhibitory Peptides in a Hydrolyzed Chicken Breast Muscle Extract", J. AGRIC. FOOD CHEM., vol. 51, no. 6, 2003, pages 1741 - 1745, XP003017892
MARUYAMA S.: "Shokuhin Yurai Protease Sogai Seibun no Seirikassei", BIOSCIENCE & INDUSTRY, vol. 59, no. 8, 2001, pages 534 - 537, XP003017893
YAMADA R. ET AL.: "Kinosei Chikusanbutsu no Genjo to Kadai Shokuniku oyobi Chikusan Fukusanbutsu Yurai no Kinosei ni tsuite -Kagakuteki Data ni Motozuita Kinosei Sozai no Teian-", CHIKUSAN CONSULTANT, vol. 41, no. 8, 2005, pages 33 - 39, XP003017894
THE JAPANESE SOCIETY ZOOTECHNICAL SCIENCE ANNUAL MEETING ABSTRACTS, vol. 106TH, 20 March 2006 (2006-03-20), pages 163 + ABSTR. NO. XI31-19, XP003017895
SOGA A. ET AL.: "Buta Collagen peptide no Ketsuatsu Josho Yokusei Sayo", THE JAPANESE SOCIETY OF NUTRITION AND FOOD SCIENCE SOKAI KOEN YOSHISHU, vol. 60TH, 1 April 2006 (2006-04-01), pages 375 + ABSTR. NO. 3J-14A, XP003017896
Attorney, Agent or Firm:
HIROSE, Takayoshi (13-3 Nishitenma 5-chome, Kita-ku, Osaka-sh, Osaka 47, JP)
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