Title:
PEPTIDE HAVING ANTIDIABETIC ACTIVITY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/277508
Kind Code:
A1
Abstract:
The present invention relates to a novel peptide having an antidiabetic activity. The peptide improves sugar metabolism and insulin resistance, inhibits amyotrophy while increasing muscle mass, and protects renal functions, and thus may be used for treating and relieving diabetes and diabetic complications.
Inventors:
SHIN MIN JEONG (KR)
JEONG IN HYEOK (KR)
JEONG IN HYEOK (KR)
Application Number:
PCT/KR2022/009198
Publication Date:
January 05, 2023
Filing Date:
June 28, 2022
Export Citation:
Assignee:
MEDI＆GENE INC (KR)
International Classes:
C07K7/06; A61K38/00; A61P3/10; C07K7/08; C07K14/00
Foreign References:
| KR20180107368A | 2018-10-02 | |||
| US20040072739A1 | 2004-04-15 |
Other References:
LEE HYE JEONG, MOON JIYOUNG, CHUNG INHYEOK, CHUNG JI HYUNG, PARK CHAN, LEE JUNG OK, HAN JEONG AH, KANG MIN JU, YOO EUN HYE, KWAK S: "ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways", THE FASEB JOURNAL, FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY, US, vol. 33, no. 12, 1 December 2019 (2019-12-01), US, pages 14825 - 14840, XP093020130, ISSN: 0892-6638, DOI: 10.1096/fj.201901440RR
ANEŽKA KAHANCOVÁ; FILIP SKLENÁŘ; PETR JEŽEK; ANDREA DLASKOVÁ: "Regulation of glucose‐stimulated insulin secretion by ATPase Inhibitory Factor 1 (IF1)", FEBS LETTERS, ELSEVIER, AMSTERDAM., NL, vol. 592, no. 6, 21 February 2018 (2018-02-21), NL , pages 999 - 1009, XP071256353, ISSN: 0014-5793, DOI: 10.1002/1873-3468.12991
GARCíA-BERMúDEZ JAVIER; CUEZVA JOSé M.: "The ATPase Inhibitory Factor 1 (IF1): A master regulator of energy metabolism and of cell survival", BIOCHIMICA ET BIOPHYSICA ACTA. BIOENERGETICS., AMSTERDAM, NL, vol. 1857, no. 8, 12 February 2016 (2016-02-12), NL , pages 1167 - 1182, XP029566616, ISSN: 0005-2728, DOI: 10.1016/j.bbabio.2016.02.004
LANCET DIABETES ENDOCRINOL, vol. 1, 2013, pages 106 - 14
ANEŽKA KAHANCOVÁ; FILIP SKLENÁŘ; PETR JEŽEK; ANDREA DLASKOVÁ: "Regulation of glucose‐stimulated insulin secretion by ATPase Inhibitory Factor 1 (IF1)", FEBS LETTERS, ELSEVIER, AMSTERDAM., NL, vol. 592, no. 6, 21 February 2018 (2018-02-21), NL , pages 999 - 1009, XP071256353, ISSN: 0014-5793, DOI: 10.1002/1873-3468.12991
GARCíA-BERMúDEZ JAVIER; CUEZVA JOSé M.: "The ATPase Inhibitory Factor 1 (IF1): A master regulator of energy metabolism and of cell survival", BIOCHIMICA ET BIOPHYSICA ACTA. BIOENERGETICS., AMSTERDAM, NL, vol. 1857, no. 8, 12 February 2016 (2016-02-12), NL , pages 1167 - 1182, XP029566616, ISSN: 0005-2728, DOI: 10.1016/j.bbabio.2016.02.004
LANCET DIABETES ENDOCRINOL, vol. 1, 2013, pages 106 - 14
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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