Title:
PEPTIDE LINKER AND LOCALIZATION METHOD FOR LOCALIZING TRANSMEMBRANE PROTEIN TO TARGET ORGANELLE, AND LOCALIZING FUSION PROTEIN
Document Type and Number:
WIPO Patent Application WO/2024/034200
Kind Code:
A1
Abstract:
Disclosed are a highly rigid peptide linker inserted between a transmembrane protein and an organelle transport signal, a fusion protein containing the same, and a localization method that includes inserting a peptide linker.
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Inventors:
SUZUKI KAZUYA (JP)
Application Number:
PCT/JP2023/016521
Publication Date:
February 15, 2024
Filing Date:
April 26, 2023
Export Citation:
Assignee:
HAMAMATSU PHOTONICS KK (JP)
International Classes:
C12N15/62; A61K31/7088; A61K35/76; A61K38/17; A61K48/00; A61P43/00; C07K2/00; C07K19/00; C12N15/63
Foreign References:
| JP2019509054A | 2019-04-04 | |||
| JP2018506285A | 2018-03-08 | |||
| JP2004325253A | 2004-11-18 | |||
| US20040072774A1 | 2004-04-15 |
Other References:
MATTHIAS A. BRUN, RUDOLF BRUN, LUC GRISS, KUI-THONG REYMOND, JOACHIM TAN, RUUD J.R.W. PIGUET, HORST PETERS, KAI VOGEL, JOHNSSON: "Semisynthesis of Fluorescent Metabolite Sensors on Cell Surfaces", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, vol. 133, no. 40, 12 October 2011 (2011-10-12), pages 16235 - 16242, XP055079261, ISSN: 00027863, DOI: 10.1021/ja206915m
DATABASE UniProtKB/TrEMBL "Putative uncharacterized protein B554R.", XP093139416
DATABASE UniProtKB/TrEMBL. "SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMXP00000045064};", XP093139419
DATABASE UniProtKB/TrEMBL "Putative uncharacterized protein B554R.", XP093139416
DATABASE UniProtKB/TrEMBL. "SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMXP00000045064};", XP093139419
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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