Title:
PEPTIDE NUCLEIC ACID THERAPEUTICS FOR TRINUCLEOTIDE REPEAT DISORDERS
Document Type and Number:
WIPO Patent Application WO/2022/261029
Kind Code:
A3
Abstract:
The present disclosure relates to compounds useful for the detection or modulation of target nucleic acids containing trinucleotide repeats. The present disclosure further relates to methods for treatment of trinucleotide repeat disorders such as polyglutamine diseases, which can include administration of oligonucleotide analogues that can bind pathogenic nucleotide repeats in DNA or RNA.
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Inventors:
STEPHAN DIETRICH A (US)
BATWAL RAMESH U (US)
BADEAU BARRY (US)
MANN WILLIAM R (US)
KILGORE AUSTIN (US)
STOLTZFUS DANI (US)
BATWAL RAMESH U (US)
BADEAU BARRY (US)
MANN WILLIAM R (US)
KILGORE AUSTIN (US)
STOLTZFUS DANI (US)
Application Number:
PCT/US2022/032402
Publication Date:
January 19, 2023
Filing Date:
June 06, 2022
Export Citation:
Assignee:
NEUBASE THERAPEUTICS INC (US)
International Classes:
C07C229/08; A61P25/14; C07K14/00
Foreign References:
| US20190055190A1 | 2019-02-21 | |||
| US20110039785A1 | 2011-02-17 | |||
| US20190022170A1 | 2019-01-24 |
Attorney, Agent or Firm:
SCHWAMB, Charles B. (US)
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