Title:
PEPTIDE WITH ANTI-OBESITY AND ANTI-DIABETIC EFFICACY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/179824
Kind Code:
A2
Abstract:
The present invention provides a peptide with an anti-obesity and/or anti-diabetic activity consisting of an amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The peptide of the present invention exhibits an excellent anti-obesity effect by inhibiting fat accumulation, reducing the sizes of adipocytes, and breaking down accumulated fat through an increase in the expression of lipolytic factors pHSL and AMPK-α1, and CGI-58, and furthermore, an excellent effect on diabetes by increasing an expression of adiponectin and AMPK which effectively reduce blood glucose and improves insulin resistance, increasing the expression of glucose transporter GLUT4, and increasing an expression of IRS-1, an insulin receptor signal transduction protein. The peptide of the present invention can be effectively used for the prevention or treatment of obesity and/or diabetes.
More Like This:
Inventors:
CHUNG YONG JI (KR)
KIM EUN MI (KR)
KIM EUN MI (KR)
Application Number:
PCT/KR2017/002884
Publication Date:
October 19, 2017
Filing Date:
March 17, 2017
Export Citation:
Assignee:
CAREGEN CO LTD (KR)
International Classes:
A61K38/08; C07K7/06
Other References:
See references of EP 3444266A4
Attorney, Agent or Firm:
YOON, Dae Woong (KR)
Download PDF:
Previous Patent: LASHING BAR FORMED OF COMPOSITE MATERIAL AND MANUFACTURING METHOD THEREFOR
Next Patent: LOW-COST ONE-WAY VALVE DEVICE
Next Patent: LOW-COST ONE-WAY VALVE DEVICE