Title:
PEPTIDES DESIGNED FOR THE DIAGNOSIS AND TREATMENT OF RHEUMATOID ARTHRITIS
Document Type and Number:
WIPO Patent Application WO2001046222
Kind Code:
A3
Abstract:
The present invention relates to peptides that mimic the immunogenic determinants of self-proteins recognised by autoimmune antibodies in a biological sample from patients suffering from rheumatoid arthritis (RA). More particularly, the present invention relates to citrulline-containing peptides, which react with the majority of the latter antibodies. Furthermore, the present invention relates to diagnostic tools for a more convenient and sensitive diagnosis of RA and to therapeutical methods to treat RA.
Inventors:
UNION ANN (BE)
MOEREELS HENRI (BE)
MEHEUS LYDIE (BE)
MOEREELS HENRI (BE)
MEHEUS LYDIE (BE)
Application Number:
PCT/EP2000/013037
Publication Date:
January 17, 2002
Filing Date:
December 20, 2000
Export Citation:
Assignee:
INNOGENETICS NV (BE)
UNION ANN (BE)
MOEREELS HENRI (BE)
MEHEUS LYDIE (BE)
UNION ANN (BE)
MOEREELS HENRI (BE)
MEHEUS LYDIE (BE)
International Classes:
A61P19/02; C07K7/08; A61K39/00; (IPC1-7): C07K7/08; A61P19/02
Domestic Patent References:
| WO1997018826A1 | 1997-05-29 | |||
| WO1998043660A1 | 1998-10-08 | |||
| WO1999028344A2 | 1999-06-10 | |||
| WO1998022503A2 | 1998-05-28 | |||
| WO1998008946A1 | 1998-03-05 |
Foreign References:
| FR2773157A1 | 1999-07-02 | |||
| US5888833A | 1999-03-30 |
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