PEPTIDES HAVING AFFINITY FOR POLYDIMETHYLSILOXANE, AND USES THEREOF

Title:

PEPTIDES HAVING AFFINITY FOR POLYDIMETHYLSILOXANE, AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2016/129695

Kind Code:

A1

Abstract:

The purpose of the present invention is to provide: a polydimethylsiloxane substrate obtained through the bonding of peptides having an affinity for polydimethylsiloxane (PDMS); a method for immobilizing a target protein on the polydimethylsiloxane substrate; peptides having an affinity for PDMS; polynucleotides for coding the peptides having an affinity for PDMS; and vectors and the like that use the polynucleotides. A polydimethylsiloxane substrate obtained through the bonding of peptides having an affinity for polydimethylsiloxane, said peptides comprising (1a) or (1b) below or fragments thereof. (1a) A peptide comprising an amino acid sequence represented by at least one sequence selected from the group consisting of SEQ ID Nos. 1 to 9. (1b) A peptide having an affinity for polydimethylsiloxane, and comprising an amino acid sequence in which one or a plurality of amino acids have been deleted, substituted and/or added in the amino acid sequence of (1a).

Inventors:

KUMADA YOICHI (JP)
OTSUKI RYOKO (JP)
AKAI RYOTA (JP)
KATAYAMA JUNKO (JP)
MATOBA KAZUTAKA (JP)

Application Number:

PCT/JP2016/054195

Publication Date:

August 18, 2016

Filing Date:

February 12, 2016

Export Citation:

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Assignee:

NAT UNIV CORP KYOTO INST OF TECH (JP)
NISSAN CHEMICAL IND LTD (JP)

International Classes:

C07K17/08; C07K14/00; C12N7/08; C12N9/00; C12N15/00

Domestic Patent References:

WO2009101807A1

2009-08-20

Foreign References:

JPS62232395A	1987-10-12
JP2010516713A	2010-05-20
JP2011168505A	2011-09-01

Other References: