Title:
PEPTIDES INDUCING ADHESIVE PROPERTY OF LACTIC ACID BACTERIUM AND USE OF SAME
Document Type and Number:
WIPO Patent Application WO/2011/021524
Kind Code:
A1
Abstract:
Disclosed are materials capable of inducing the adhesive property of a lactic acid bacterium and use of the same. Specifically disclosed is a peptide having an amino acid sequence selected from the group consisting of the following sequences and being capable of inducing the adhesive property of a lactic acid bacterium: SCDRNGIC (SEQ ID NO:1), DRNGICKG (SEQ ID NO:2), RNGICKG (SEQ ID NO:3), NGICKG (SEQ ID NO:4), QRCVNLQA (SEQ ID NO:5), QRCVNLQ (SEQ ID NO:6), QRCVNL (SEQ ID NO:7), QRCVN (SEQ ID NO:8), TFTKIQRK (SEQ ID NO:9), TKIQRKDF (SEQ ID NO:10), IQRKDFAG (SEQ ID NO:11), IKKFTFRN (SEQ ID NO:12), KFTFRNVK (SEQ ID NO:13), KFTFRNV (SEQ ID NO:14), FTFRNVK (SEQ ID NO:15), KFTFRN (SEQ ID NO:16), FTFRNV (SEQ ID NO:17), TFRNVK (SEQ ID NO:18), KFTFR (SEQ ID NO:19), FTFRN (SEQ ID NO:20), TFRNV (SEQ ID NO:21), FRNVK (SEQ ID NO:22), GNFRASDN (SEQ ID NO:23), GNFRASD (SEQ ID NO:24), GNFRAS (SEQ ID NO:25), GNFRA (SEQ ID NO:26), RVKRITVE (SEQ ID NO:27), KRITVENS (SEQ ID NO:28), SLNLPQLK (SEQ ID NO:29), LNLPQLK (SEQ ID NO:30), NLPQLKEL (SEQ ID NO:31), NLPQLKE (SEQ ID NO:32), PQLKEL (SEQ ID NO:33), LPQLK (SEQ ID NO:34), PQLKE (SEQ ID NO:35), QLKEL (SEQ ID NO:36), HVRGQQVQ (SEQ ID NO:37) and RLSVSECH (SEQ ID NO:38).
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Inventors:
HONDA HIROYUKI (JP)
OKOCHI MINA (JP)
SUGITA TOMOYA (JP)
OKOCHI MINA (JP)
SUGITA TOMOYA (JP)
Application Number:
PCT/JP2010/063478
Publication Date:
February 24, 2011
Filing Date:
August 09, 2010
Export Citation:
Assignee:
UNIV NAGOYA NAT UNIV CORP (JP)
HONDA HIROYUKI (JP)
OKOCHI MINA (JP)
SUGITA TOMOYA (JP)
HONDA HIROYUKI (JP)
OKOCHI MINA (JP)
SUGITA TOMOYA (JP)
International Classes:
C07K14/705; A23L1/30; A61K38/00; A61P1/00; A61P3/06; A61P35/00; C07K7/06; C12N1/00; C12N1/20
Foreign References:
| JP2008169198A | 2008-07-24 | |||
| JP2002514083A | 2002-05-14 |
Other References:
TOHNO M. ET AL: "Advanced molecular immunoassay system for immunobiotic lactic acid bacteria using a transfectant of Toll-like receptor 2", ANIM. SCI. J., vol. 78, no. 2, 2007, pages 195 - 205
TOHNO M. ET AL.: "A swine toll-like receptor 2-expressing transfectant as a potential primary screening system for immunobiotic microorganisms", FEMS IMMUNOL. MED. MICROBIOL., vol. 44, no. 3, 2005, pages 283 - 288, XP025316721, DOI: doi:10.1016/j.femsim.2004.12.009
HIROYUKI HONDA ET AL.: "Tansa Kinosei Peptide no Tansaku: Peptide Informatics", BIOTECHNOLOGY, vol. 87, no. 6, 2009, pages 280 - 282
OKOCHI M. ET AL.: "Peptide array-based screening of human mesenchymal stem cell- adhesive peptides derived from fibronectin type III domain", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 371, no. 1, 2008, pages 85 - 89, XP022639251, DOI: doi:10.1016/j.bbrc.2008.04.019
TOHNO M. ET AL.: "A swine toll-like receptor 2-expressing transfectant as a potential primary screening system for immunobiotic microorganisms", FEMS IMMUNOL. MED. MICROBIOL., vol. 44, no. 3, 2005, pages 283 - 288, XP025316721, DOI: doi:10.1016/j.femsim.2004.12.009
HIROYUKI HONDA ET AL.: "Tansa Kinosei Peptide no Tansaku: Peptide Informatics", BIOTECHNOLOGY, vol. 87, no. 6, 2009, pages 280 - 282
OKOCHI M. ET AL.: "Peptide array-based screening of human mesenchymal stem cell- adhesive peptides derived from fibronectin type III domain", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 371, no. 1, 2008, pages 85 - 89, XP022639251, DOI: doi:10.1016/j.bbrc.2008.04.019
Attorney, Agent or Firm:
HAGINO Mikiharu (JP)
Kanji Hagino (JP)
Kanji Hagino (JP)
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