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Title:
PERFLUORONATED CYCLE-CONTAINING TERTIARY AMINES USED AS A BASIS FOR GAS-CONVEYING EMULSIONS AND DEVICE FOR THE PRODUCTION THEREOF
Document Type and Number:
WIPO Patent Application WO/2002/053525
Kind Code:
A1
Abstract:
The inventive perfluoronated cycle-containing tertiary amines (PFCTA) of general formula (1) where n=1 or 2; m=2 or 3 X represents or , at n=2 X represents are used as a basis for gas conveying emulsions. PFCTA is a group of compounds near to perfluor-N-(4-methylcyclohexyl)-piperidine with respect to the properties thereof, in particular with respect to a critical solution temperature in hexane. Said compounds are used in a mixture, thereby producing a range of compounds which exhibit gradually changing characteristics and making it possible to obtain highly uniform fluorocarbon phases of the emulsions and to increase the stability of emulsion particles which are stabilised with the aid of ethylene oxide-propylene oxide block polymers without being toxic for small and large animals. The PFCTA is produced by electrochemical fluorination of n-piperidine heptane fluor toluene in anhydrous hydrogen fluoride. The use of said PFCTA mixture instead of the individual perfluor-N-(4-methylcyclohexyl)-piperidine makes it possible to simplify, accelerate and lower the price of the production of perfluoronated organic compounds and extend the use of gas conveying emulsions produced on the basis thereof.

Inventors:
GERVITS LEV LVOVICH (RU)
MAKAROV KIRILL NIKOLAEVICH (RU)
MAEVSKY EVGENY ILIICH (RU)
IVANITSKY GENRIKH ROMANOVICH (RU)
PUSHKIN SERGEI JURIEVICH (RU)
MASLENNIKOV IGOR ALEXEEVICH (RU)
Application Number:
PCT/RU2000/000547
Publication Date:
July 11, 2002
Filing Date:
December 29, 2000
Export Citation:
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Assignee:
OTKRYTOE AKTSIONERNOE OBSCHEST (RU)
GERVITS LEV LVOVICH (RU)
MAKAROV KIRILL NIKOLAEVICH (RU)
MAEVSKY EVGENY ILIICH (RU)
IVANITSKY GENRIKH ROMANOVICH (RU)
PUSHKIN SERGEI JURIEVICH (RU)
MASLENNIKOV IGOR ALEXEEVICH (RU)
International Classes:
A01N1/02; A61K9/00; A61K9/107; A61K31/13; A61K31/40; A61K31/445; A61K31/452; A61P7/00; A61P7/04; A61P7/08; A61P9/08; A61P41/00; A61P43/00; C07C211/37; C07D207/08; C07D207/10; C07D211/38; C07D211/66; C25B3/28; (IPC1-7): C07C211/37; C07D211/66; A61K31/13; A61K31/40; A61K31/452; A61K31/445; A61K9/107; C25B3/08; A61P7/00; A61P7/04; A61P7/08; A61P43/00; A01N1/02
Foreign References:
GB2125787A1984-03-14
US2631151A1953-03-10
DE4019061A11991-03-07
AU517547B21981-08-06
RU2088217C11997-08-27
US5214214A1993-05-25
GB2201674A1988-09-07
Other References:
See also references of EP 1354868A4
Attorney, Agent or Firm:
Agureev, Alexandr Pavlovich (5/2 Moscow, 5, RU)
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