Title:
PERIOSTIN AND PKM2 SECRETION PROMOTER
Document Type and Number:
WIPO Patent Application WO/2019/077810
Kind Code:
A1
Abstract:
Provided is an agent or composition useful for the proliferation of myocytes, etc. The agent or composition comprises component (A) which is at least one member selected from acteoside, echinacoside and salts thereof and component (B) which is at least one member selected from periostin and PKM2.
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Inventors:
TOHDA CHIHIRO (JP)
KOTANI ATSUSHI (JP)
KOTANI ATSUSHI (JP)
Application Number:
PCT/JP2018/025119
Publication Date:
April 25, 2019
Filing Date:
July 02, 2018
Export Citation:
Assignee:
UNIV OF TOYAMA (JP)
International Classes:
A61K31/7028; A23L33/105; A61K36/64; A61K38/16; A61K38/45; A61P21/00; A61P25/00; A61P43/00
Foreign References:
| US20110144040A1 | 2011-06-16 | |||
| JP2016521717A | 2016-07-25 | |||
| US20100166827A1 | 2010-07-01 |
Other References:
KODANI, ATSUSHI ET AL., CHRONIC SPINAL CORD INJURY REPAIR MEDIATED BY SKELETAL MUSCLE-SECRETED NEW MYOKINE, 3 July 2017 (2017-07-03), Retrieved from the Internet [retrieved on 20180816]
TANAKA, JUNJI ET AL.: "New functions of Cistanche tubulosa extract for health: anti-anoxic effect and preventive effect against radiation injury of Cistanche tubulosa extract", FOOD STYLE, vol. 12, no. 7, 2008, pages 21 - 23, ISSN: 1343-9502
GENOVESE, TIZIANA ET AL.: "Efficacy of treatment with verbascoside, biotecnologically produced by Syringa vulgaris plant cell cultures in an experimental mice model of spinal cord trauma", NAUNYN-SCHMIEDEBERG'SARCHIVES OF PHARMACOLOGY, vol. 382, no. 4, 2010, pages 331 - 345, XP019838864, ISSN: 0028-1298
MATSUNAGA, EIJI ET AL.: "Periostin, a neurite outgrowth-promoting fator, is expressed at high levels in the primate cerebral cortex", DEVELOPMENT, GROWTH & DIFFERENTIATION, vol. 57, no. 3, 1 April 2015 (2015-04-01), pages 200 - 208, XP055596991, ISSN: 1440-169X
SHIH CHUNG-HSUAN ET AL.: "Astroglial-derived periostin promotes axonal regeneration after spinal cord injury", JOURNAL OF NEUROSCIENCE, vol. 34, no. 7, 2014, pages 2438 - 2443, XP055596993, ISSN: 0270-6474
GAO, ZHIHUA ET AL.: "Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 110, no. 33, 13 August 2013 (2013-08-13), pages 13570 - 13575, XP055596994, ISSN: 0027-8424
TANAKA, JUNJI ET AL.: "New functions of Cistanche tubulosa extract for health: anti-anoxic effect and preventive effect against radiation injury of Cistanche tubulosa extract", FOOD STYLE, vol. 12, no. 7, 2008, pages 21 - 23, ISSN: 1343-9502
GENOVESE, TIZIANA ET AL.: "Efficacy of treatment with verbascoside, biotecnologically produced by Syringa vulgaris plant cell cultures in an experimental mice model of spinal cord trauma", NAUNYN-SCHMIEDEBERG'SARCHIVES OF PHARMACOLOGY, vol. 382, no. 4, 2010, pages 331 - 345, XP019838864, ISSN: 0028-1298
MATSUNAGA, EIJI ET AL.: "Periostin, a neurite outgrowth-promoting fator, is expressed at high levels in the primate cerebral cortex", DEVELOPMENT, GROWTH & DIFFERENTIATION, vol. 57, no. 3, 1 April 2015 (2015-04-01), pages 200 - 208, XP055596991, ISSN: 1440-169X
SHIH CHUNG-HSUAN ET AL.: "Astroglial-derived periostin promotes axonal regeneration after spinal cord injury", JOURNAL OF NEUROSCIENCE, vol. 34, no. 7, 2014, pages 2438 - 2443, XP055596993, ISSN: 0270-6474
GAO, ZHIHUA ET AL.: "Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 110, no. 33, 13 August 2013 (2013-08-13), pages 13570 - 13575, XP055596994, ISSN: 0027-8424
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
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