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Title:
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR CONTROLLERS
Document Type and Number:
WIPO Patent Application WO/1999/012534
Kind Code:
A1
Abstract:
Peroxisome proliferator-activated receptor (PPAR) controllers containing as the active ingredient compounds represented by general formula (I), salts of the same, or hydrates of both (wherein each symbol is as defined in the description). The compounds exhibit control effects against PPAR and are therefore useful as, e.g., antihyperglycemic drugs, antihyperlipidemic drugs, or preventive and/or therapeutic agents for metabolic diseases such as diabetes, obesity, syndrome X, hypercholesterolemia and hyperlipo-proteinemia; hyperlipemia, arteriosclerosis, circulatory diseases, polyphagy, and ischemic heart diseases.

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Inventors:
TAJIMA HISAO (JP)
NAKAYAMA YOSHISUKE (JP)
FUKUSHIMA DAIKICHI (JP)
Application Number:
PCT/JP1998/003930
Publication Date:
March 18, 1999
Filing Date:
September 02, 1998
Export Citation:
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Assignee:
ONO PHARMACEUTICAL CO (JP)
TAJIMA HISAO (JP)
NAKAYAMA YOSHISUKE (JP)
FUKUSHIMA DAIKICHI (JP)
International Classes:
C07D257/04; (IPC1-7): A61K31/17; A61K31/41; C07D257/04
Domestic Patent References:
WO1995026188A11995-10-05
WO1995024901A11995-09-21
WO1994004153A11994-03-03
WO1993008171A11993-04-29
WO1993008169A11993-04-29
WO1996040128A21996-12-19
WO1996033724A21996-10-31
WO1996023884A21996-08-08
Foreign References:
JPH06211814A1994-08-02
JPH06184086A1994-07-05
JPH0672985A1994-03-15
JPH09124691A1997-05-13
JPH09110691A1997-04-28
JPH0931061A1997-02-04
JPH0841053A1996-02-13
JPH07316055A1995-12-05
EP0635263A21995-01-25
EP0628313A11994-12-14
JPH06287182A1994-10-11
EP0520423A21992-12-30
Attorney, Agent or Firm:
Ohie, Kunihisa (Nihonbashi-Ningyocho 2-chome Chuo-ku Tokyo, JP)
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