Title:
PERSULFATED OLIGOSACCHARIDE ACTING ON SELECTINS AND CHEMOKINE
Document Type and Number:
WIPO Patent Application WO/2004/011662
Kind Code:
A1
Abstract:
A persulfated oligosaccharide acting on selectins and chemokine. Namely, a saccharide compound interacting with L-selectin, P-selectin and chemokine; medicinal compositions and remedies or preventives for diseases the onset of which relates to biological phenomena mediated respectively by L-selectin, P-selectin and chemokine.
Inventors:
MIYASAKA MASAYUKI (JP)
KAWASHIMA HIROTO (JP)
KAWASHIMA HIROTO (JP)
Application Number:
PCT/JP2003/000823
Publication Date:
February 05, 2004
Filing Date:
January 29, 2003
Export Citation:
Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
MIYASAKA MASAYUKI (JP)
KAWASHIMA HIROTO (JP)
MIYASAKA MASAYUKI (JP)
KAWASHIMA HIROTO (JP)
International Classes:
A61K31/702; A61P9/00; A61P29/00; A61P35/04; A61P37/08; A61P43/00; C07H11/00; C12P11/00; C12P19/14; C07H13/04; (IPC1-7): C12P19/14; C07H11/00; C08B37/00; A61K31/7024; A61P9/00; A61P29/00; A61P35/04; A61P37/08; A61P43/00
Other References:
KAWASHIMA H, et al., "Oversulfated Chondroitin/Dermatan Sulfates Containing GlcAbetal/IdoAal-3 GalNAc(4,6-0-disulfate) Interact with L-and P-selectin and Chemokines." J. Biol. Chem., April 2002, Vol. 277, No. 15, pages 12921 to 12930
Kazuyuki ARATA et al., "L-Selectin to CD44 no Kyotsu ligand Chondroitin Ryusan Proteoglycan", Protein, Nucleic acid and Enzyme, 10 December 2002, Vol. 47, No. 16, pages 2214 to 2220
Kazuyuki ARATA et al., "L-Selectin to CD44 no Kyotsu ligand Chondroitin Ryusan Proteoglycan", Protein, Nucleic acid and Enzyme, 10 December 2002, Vol. 47, No. 16, pages 2214 to 2220
Attorney, Agent or Firm:
Hosoda, Yoshinori c/o Hosoda International Patent Office (OMM Building 5th Floor P.O.Box 26, 7-31,
Otemae 1-chome, Chuo-k, Osaka-shi Osaka, JP)
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