Title:
PEYER'S PATCH ACTIVATOR
Document Type and Number:
WIPO Patent Application WO/2014/054421
Kind Code:
A1
Abstract:
The present invention provides a Peyer's patch activator containing polysaccharides obtained from sugar cane as active components. The polysaccharides mainly comprise α-glucans, and have a peak molecular weight in the range of 720,000-1,080,000. The ratio of glucose, relative to the total constituent saccharides, is equal to or greater than 80%. The ratio of non-reducing terminal glucose is 20-30%, and the ratio of α-1,6-bonded glucose is 15-25%.
Inventors:
YAMADA HARUKI (JP)
KIYOHARA HIROAKI (JP)
OTOGURO KAZUHIKO (JP)
ISHIYAMA AKI (JP)
IWATSUKI MASATO (JP)
OMURA SATOSHI (JP)
MIZU MASAMI (JP)
KAWAI TOSHIKAZU (JP)
KASHIMURA JUN (JP)
KOGE KENJI (JP)
KIYOHARA HIROAKI (JP)
OTOGURO KAZUHIKO (JP)
ISHIYAMA AKI (JP)
IWATSUKI MASATO (JP)
OMURA SATOSHI (JP)
MIZU MASAMI (JP)
KAWAI TOSHIKAZU (JP)
KASHIMURA JUN (JP)
KOGE KENJI (JP)
Application Number:
PCT/JP2013/075152
Publication Date:
April 10, 2014
Filing Date:
September 18, 2013
Export Citation:
Assignee:
MITSUI SUGAR CO (JP)
KITASATO INST (JP)
KITASATO INST (JP)
International Classes:
A23K1/16; A61K31/716; A23L1/30; A61K36/899; A61P33/06; A61P37/04; A61P43/00; C08B30/04
Foreign References:
| JP2000297046A | 2000-10-24 | |||
| JP2000297046A | 2000-10-24 | |||
| JP2003063975A | 2003-03-05 |
Other References:
MOSHIRA EL-ABASY ET AL.: "Immunostimulating and Growth-Promoting Effects of Sugar Cane Extract (SCE) in Chickens", JOURNAL OF VETERINARY MEDICAL SCIENCE, vol. 64, no. LL, 2002, pages 1061 - 1063, XP055245524
MOSHIRA EL-ABASY ET AL.: "Protective Effects of Sugar Cane Extracts (SCE) on Eimeria tenella Infection in Chickens", JOURNAL OF VETERINARY MEDICAL SCIENCE, vol. 65, no. 8, 2003, pages 865 - 871, XP055245528
ASKLING H H ET AL.: "Management of imported malaria in Europe", MALAR J, vol. 11, 17 September 2012 (2012-09-17), XP055245530
SHUICHI KAMINOGAWA ET AL.: "Research on the evaluation of the effects of so-called health food - establishment of evaluation methods for the immunoregulatory and allergy prevention functions of food", RESEARCH ON THE EVALUATION OF THE EFFECTS OF SO-CALLED HEALTH FOOD HEISEI 17 NENDO SOKATSU BUNTAN KENKYU HOKOKUSHO, 2006, pages 11 - 20, XP008178819
LI X ET AL.: "Activation of the classical complement pathway by a polysaccharide from sugar cane", IMMUNOPHARMACOLOGY, vol. 5, no. 1, 1982, BETHESDA, MD, USA., pages 31 - 8, XP023816063
YOKO NAKASONE: "Water soluble polysaccharides in cane juice obtained by the diffusion system", THE SCIENCE BULLETIN OF THE COLLEGE OF AGRICULTURE, 1980, UNIVERSITY OF THE RYUKYUS, pages 175 - 181, XP008178818
T. HONG; T. MATSUMOTO; H. KIYOHARA; H. YAMADA: "Enhanced production of hematopoietic growth factors through T cell activation in Peyer's patches by oral administration of Kampo (Japanese herbal) medicines, 'Juzen-taiho-to", PHYTOMEDICINE, vol. 5, 1998, pages 353 - 360
HIROAKI KIYOHARA; TOSHIAKE MATSUZAKI; TSUKASA MATSUMOTO; TAKAYUKI NAGAI; HARUKI YAMADA, YAKUGAKU ZASSHI, vol. 128, no. 5, 2008, pages 709 - 719
MOSHIRA EL-ABASY ET AL.: "Protective Effects of Sugar Cane Extracts (SCE) on Eimeria tenella Infection in Chickens", JOURNAL OF VETERINARY MEDICAL SCIENCE, vol. 65, no. 8, 2003, pages 865 - 871, XP055245528
ASKLING H H ET AL.: "Management of imported malaria in Europe", MALAR J, vol. 11, 17 September 2012 (2012-09-17), XP055245530
SHUICHI KAMINOGAWA ET AL.: "Research on the evaluation of the effects of so-called health food - establishment of evaluation methods for the immunoregulatory and allergy prevention functions of food", RESEARCH ON THE EVALUATION OF THE EFFECTS OF SO-CALLED HEALTH FOOD HEISEI 17 NENDO SOKATSU BUNTAN KENKYU HOKOKUSHO, 2006, pages 11 - 20, XP008178819
LI X ET AL.: "Activation of the classical complement pathway by a polysaccharide from sugar cane", IMMUNOPHARMACOLOGY, vol. 5, no. 1, 1982, BETHESDA, MD, USA., pages 31 - 8, XP023816063
YOKO NAKASONE: "Water soluble polysaccharides in cane juice obtained by the diffusion system", THE SCIENCE BULLETIN OF THE COLLEGE OF AGRICULTURE, 1980, UNIVERSITY OF THE RYUKYUS, pages 175 - 181, XP008178818
T. HONG; T. MATSUMOTO; H. KIYOHARA; H. YAMADA: "Enhanced production of hematopoietic growth factors through T cell activation in Peyer's patches by oral administration of Kampo (Japanese herbal) medicines, 'Juzen-taiho-to", PHYTOMEDICINE, vol. 5, 1998, pages 353 - 360
HIROAKI KIYOHARA; TOSHIAKE MATSUZAKI; TSUKASA MATSUMOTO; TAKAYUKI NAGAI; HARUKI YAMADA, YAKUGAKU ZASSHI, vol. 128, no. 5, 2008, pages 709 - 719
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
Yoshiki Hasegawa (JP)
Yoshiki Hasegawa (JP)
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