Title:
PHARMACEUTICAL COMPOSITION COMPRISING BICYCLE DERIVATIVE AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER
Document Type and Number:
WIPO Patent Application WO/2023/229293
Kind Code:
A1
Abstract:
The present invention relates a bicycle derivative and a pharmaceutical composition comprising same as an active ingredient for the prevention or treatment of cancer. Found to have ACC inhibitory activity involved in the inhibitory mechanism against tumor proliferation and metastasis, the bicycle derivative disclosed in the description is expected to be useful for preventing or treating cancer.
Inventors:
IM CHUN YOUNG (KR)
MIN SANG-HYUN (KR)
KIM NAM HUI (KR)
HWANG HEE-JONG (KR)
OH BAE JUN (KR)
HONG EUNMI (KR)
WOO SEO YEON (KR)
HAN YE RI (KR)
DO HYUN JU (KR)
JANG TAE-HO (KR)
LEE SEUL (KR)
KIM NAM DOO (KR)
LEE JEE-YOUNG (KR)
YU JI HOON (KR)
LEE HA-YEON (KR)
KIM YOUNG-KYU (KR)
PARK SANG-WOOK (KR)
SHIN SUNHYE (KR)
CHA EUNJU (KR)
HWANG JI SUN (KR)
SEO CHANG HOON (KR)
YEOM YOUNG IL (KR)
LEE DONG CHUL (KR)
PARK KYUNG CHAN (KR)
KIM CHA YEON (KR)
KOO HAN (KR)
MIN SANG-HYUN (KR)
KIM NAM HUI (KR)
HWANG HEE-JONG (KR)
OH BAE JUN (KR)
HONG EUNMI (KR)
WOO SEO YEON (KR)
HAN YE RI (KR)
DO HYUN JU (KR)
JANG TAE-HO (KR)
LEE SEUL (KR)
KIM NAM DOO (KR)
LEE JEE-YOUNG (KR)
YU JI HOON (KR)
LEE HA-YEON (KR)
KIM YOUNG-KYU (KR)
PARK SANG-WOOK (KR)
SHIN SUNHYE (KR)
CHA EUNJU (KR)
HWANG JI SUN (KR)
SEO CHANG HOON (KR)
YEOM YOUNG IL (KR)
LEE DONG CHUL (KR)
PARK KYUNG CHAN (KR)
KIM CHA YEON (KR)
KOO HAN (KR)
Application Number:
PCT/KR2023/006780
Publication Date:
November 30, 2023
Filing Date:
May 18, 2023
Export Citation:
Assignee:
DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR)
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
International Classes:
C07C215/48; C07C219/28; C07C229/38; C07C235/66; C07D213/61; C07D215/54; C07D231/56; C07D239/72; C07D239/80; C07D241/42
Domestic Patent References:
| WO2017049409A1 | 2017-03-30 | |||
| WO2014055461A1 | 2014-04-10 | |||
| WO2015132143A1 | 2015-09-11 |
Foreign References:
| CN103804179A | 2014-05-21 |
Other References:
LÓPEZ-IGLESIAS BEATRIZ, PÉREZ CONCEPCIÓN, MORALES-GARCÍA JOSÉ A., ALONSO-GIL SANDRA, PÉREZ-CASTILLO ANA, ROMERO ALEJANDRO, LÓPEZ M: "New Melatonin– N , N -Dibenzyl( N -methyl)amine Hybrids: Potent Neurogenic Agents with Antioxidant, Cholinergic, and Neuroprotective Properties as Innovative Drugs for Alzheimer’s Disease", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 57, no. 9, 8 May 2014 (2014-05-08), US , pages 3773 - 3785, XP093110923, ISSN: 0022-2623, DOI: 10.1021/jm5000613
Attorney, Agent or Firm:
LEE, Won Hee (KR)
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