Title:
PHARMACEUTICAL COMPOSITION COMPRISING COMBINATION OF COMPOUND HAVING NUTRIENT DIGESTION/ABSORPTION INHIBITORY ACTIVITY AND CYCLOHEXANECARBOXAMIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2010/098298
Kind Code:
A1
Abstract:
Disclosed is a pharmaceutical composition which comprises a combination of a compound having a nutrient digestion/absorption inhibitory activity, a pharmaceutically acceptable salt thereof or a solvate of the compound or salt, and a compound represented by formula (I), a pharmaceutically acceptable salt thereof or a solvate of the compound or salt. The pharmaceutical composition is found to significantly reduce the body weight. Consequently, the pharmaceutical composition is useful for treatment or prevention of obesity and obesity-related diseases.
(In the formula, R1 represents an alkyl group; R2 represents hydrogen or an alkyl group; and Z represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted amino group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted cyclic hydrocarbon group, or a substituted or unsubstituted heterocyclic group.)
Inventors:
YUKIOKA HIDEO (JP)
Application Number:
PCT/JP2010/052677
Publication Date:
September 02, 2010
Filing Date:
February 23, 2010
Export Citation:
Assignee:
SHIONOGI & CO (JP)
YUKIOKA HIDEO (JP)
YUKIOKA HIDEO (JP)
International Classes:
A61K31/44; A61K31/18; A61K31/365; A61K31/5375; A61K45/00; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P9/12; A61P15/08; A61P19/02; A61P19/06; A61P25/20; A61P35/00
Domestic Patent References:
| WO2008026563A1 | 2008-03-06 | |||
| WO2001037826A1 | 2001-05-31 | |||
| WO2005080348A1 | 2005-09-01 |
Foreign References:
| JP2006502131A | 2006-01-19 | |||
| JP2005533849A | 2005-11-10 | |||
| JP2005526732A | 2005-09-08 |
Attorney, Agent or Firm:
TAKAYAMA, Hirotsugu et al. (JP)
Hiromitsu Takayama (JP)
Hiromitsu Takayama (JP)
Download PDF: