PHARMACEUTICAL COMPOSITION COMPRISING HIGH CONTENT OF ACTIVE INGREDIENTS DERIVED FROM NATURAL SUBSTANCES

Title:

PHARMACEUTICAL COMPOSITION COMPRISING HIGH CONTENT OF ACTIVE INGREDIENTS DERIVED FROM NATURAL SUBSTANCES

Document Type and Number:

WIPO Patent Application WO/2022/114796

Kind Code:

A1

Abstract:

The present disclosure relates to a formulation, preferably a tablet, comprising a high content of herbal extracts of Clematis florida, Trichosanthes kirilowii Maxim, and Prunella vulgaris var. lilacina Nakai as active ingredients useful for treating or alleviating arthritis. The formulation of the present disclosure comprises a high content of active ingredients and has a small size, thereby being very convenient to administer, having a release pattern that can be taken twice a day, and exhibiting excellent release properties, and in particular, there is no significant difference in a dissolution pattern at various pHs, thereby reducing interpersonal and interindividual variations.

Inventors:

KANG MINSEOK (KR)
JUNG YOON-SEOK (KR)
LEE SOO MIN (KR)
KIM DO-YUN (KR)
MOON SEUNG-KWAN (KR)
JEONG DA-HEE (KR)
JUNG EUN-HA (KR)
KIM JEONG-HOON (KR)
PARK YEO-JIN (KR)
YOO HUNSEUNG (KR)
CHOI WONJAE (KR)
SONG KWANG-HO (KR)

Application Number:

PCT/KR2021/017445

Publication Date:

June 02, 2022

Filing Date:

November 24, 2021

Export Citation:

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Assignee:

SK CHEMICALS CO LTD (KR)

International Classes:

A61K9/20; A61K9/48; A61K36/428; A61K36/536; A61K36/716; A61P29/00; A61Q19/02

Foreign References:

KR20110009379A	2011-01-28
KR20150091636A	2015-08-12
KR20080099058A	2008-11-12
KR20180083239A	2018-07-20

Other References:

HARTOG, A. ; HOUGEE, S. ; FABER, J. ; SANDERS, A. ; ZUURMAN, C. ; SMIT, H.F. ; VAN DER KRAAN, P.M. ; HOIJER, M.A. ; GARSSEN, J.: "The multicomponent phytopharmaceutical SKI306X inhibits in vitro cartilage degradation and the production of inflammatory mediators", PHYTOMEDICINE, vol. 15, no. 5, 15 May 2008 (2008-05-15), AMSTERDAM, NL , pages 313 - 320, XP022609712, ISSN: 0944-7113, DOI: 10.1016/j.phymed.2007.09.005

Attorney, Agent or Firm:

PHIL & ONZI INT'L PATENT & LAW FIRM (KR)

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