Title:
PHARMACEUTICAL COMPOSITION COMPRISING MACROCOSINE COMPOUND AND METHOD FOR PREPARING MACROCOSINE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2022/245150
Kind Code:
A1
Abstract:
The present invention provides a method for preparing a macrocosine compound, and a pharmaceutical composition for the treatment and prevention of infection of a specific strain comprising a macrocosine compound, a solvate thereof, a hydrate thereof, a prodrug thereof, an isomer thereof, or a pharmaceutically acceptable salt thereof as an active ingredient. In addition, the present invention provides an anti-inflammatory composition comprising the macrocosine compound, a solvate thereof, a hydrate thereof, a prodrug thereof, an isomer thereof, or a pharmaceutically acceptable salt thereof as an active ingredient.
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Inventors:
HWANG HEE-JONG (KR)
SON YOUNG-JIN (KR)
KIM DAHYUN (KR)
LEE JUSUK (KR)
CLOVIS SHYAKA (KR)
CIUFOLINI MARCO (CA)
SON YOUNG-JIN (KR)
KIM DAHYUN (KR)
LEE JUSUK (KR)
CLOVIS SHYAKA (KR)
CIUFOLINI MARCO (CA)
Application Number:
PCT/KR2022/007173
Publication Date:
November 24, 2022
Filing Date:
May 19, 2022
Export Citation:
Assignee:
A&J SCIENCE CO LTD (KR)
International Classes:
A61K38/12; A61K38/16; A61K45/06; A61P31/04; A61P31/06; C07K1/06; C07K14/32
Domestic Patent References:
| WO2015063711A1 | 2015-05-07 |
Foreign References:
| KR20040000404A | 2004-01-03 |
Other References:
BOWERS ALBERT A., ACKER MICHAEL G., YOUNG TRAVIS S., WALSH CHRISTOPHER T.: "Generation of Thiocillin Ring Size Variants by Prepeptide Gene Replacement and in Vivo Processing by Bacillus cereus", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, vol. 134, no. 25, 27 June 2012 (2012-06-27), pages 10313 - 10316, XP055975216, ISSN: 0002-7863, DOI: 10.1021/ja302820x
BENNALLACK PHILIP ROSS, GRIFFITTS JOEL S, CO-CHAIR, ROBISON RICHARD A, CO-CHAIR, GROSE JULIANNE H, JOHNSON STEVEN M, BUNDY BRADL: "Genetic and biochemical analysis of the micrococcin biosynthetic pathway", PROQUEST DISSERTATIONS PUBLISHING, 1 January 2016 (2016-01-01), XP093005032, ISBN: 978-1-369-47873-0, [retrieved on 20221205]
AULAKH VIRENDER S., CIUFOLINI MARCO A.: "Total Synthesis and Complete Structural Assignment of Thiocillin I", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, vol. 133, no. 15, 20 April 2011 (2011-04-20), pages 5900 - 5904, XP093005036, ISSN: 0002-7863, DOI: 10.1021/ja110166x
ORG. LETT, vol. 22, no. 6, 2020, pages 2365 - 2370
BENNALLACK PHILIP ROSS, GRIFFITTS JOEL S, CO-CHAIR, ROBISON RICHARD A, CO-CHAIR, GROSE JULIANNE H, JOHNSON STEVEN M, BUNDY BRADL: "Genetic and biochemical analysis of the micrococcin biosynthetic pathway", PROQUEST DISSERTATIONS PUBLISHING, 1 January 2016 (2016-01-01), XP093005032, ISBN: 978-1-369-47873-0, [retrieved on 20221205]
AULAKH VIRENDER S., CIUFOLINI MARCO A.: "Total Synthesis and Complete Structural Assignment of Thiocillin I", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, vol. 133, no. 15, 20 April 2011 (2011-04-20), pages 5900 - 5904, XP093005036, ISSN: 0002-7863, DOI: 10.1021/ja110166x
ORG. LETT, vol. 22, no. 6, 2020, pages 2365 - 2370
Attorney, Agent or Firm:
PLUS INTERNATIONAL IP LAW FIRM (KR)
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