PHARMACEUTICAL COMPOSITION PARTICLES AND ORALLY DISINTEGRATING PREPARATION INCLUDING SAME

WIPO Patent Application WO/2017/146053

A1

Provided are: pharmaceutical composition particles and an orally disintegrating tablet including the same which are capable of achieving both the masking of unpalatable taste and an improvement in elution properties; and a method for producing pharmaceutical composition particles. This pharmaceutical composition particle comprises: a core particle including a water-soluble gelling-swelling substance; an intermediate layer that includes a drug and that covers the outer side of the core particle; and an outer layer that includes a water-insoluble substance and that covers the outer side of the intermediate layer. This orally disintegrating tablet comprises said pharmaceutical composition particles.

HAYASHIDA TOMOHIRO (JP)
HOASHI YOHEI (JP)
IJITSU SHIN (JP)
NAKANO YOSHIO (JP)
YAMAZAKI JUNJI (JP)
INOUE KATSUHISA (JP)
AIZAWA ATSUSHI (JP)

PCT/JP2017/006389

August 31, 2017

February 21, 2017

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NIPRO CORP (JP)
ZENSEI PHARMACEUTICAL IND CO LTD (JP)

A61K47/00; A61K9/14; A61K9/26; A61K31/136; A61K45/00; A61K47/32; A61K47/36; A61K47/38; A61P1/00; A61P1/04; A61P1/06; A61P1/10; A61P1/12; A61P1/14; A61P1/16; A61P3/02; A61P3/06; A61P3/10; A61P5/00; A61P5/38; A61P7/04; A61P7/10; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P9/12; A61P11/08; A61P11/10; A61P11/14; A61P11/16; A61P13/00; A61P19/06; A61P19/10; A61P21/00; A61P23/02; A61P25/00; A61P25/06; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P29/00; A61P31/00; A61P31/04; A61P35/00; A61P37/06; A61P43/00

JP2004231520A	2004-08-19
JP2002212062A	2002-07-31
JP2010534203A	2010-11-04
JPH10504300A	1998-04-28

See also references of EP 3431107A4

AKAOKA Kazuo et al. (JP)

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