Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING AGE-RELATED MACULAR DEGENERATION
Document Type and Number:
WIPO Patent Application WO/2022/240165
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating age-related macular degeneration. Age-related macular degeneration is the number one cause of adult blindness in developed countries. Dry age-related macular degeneration, which is the more common type of age-related macular degeneration, is currently the most serious problem since there is no cure for the disease. The pharmaceutical composition and a food composition according to the present invention comprising nicotinamide or a derivative thereof as an active ingredient have an effect of significantly relieving, structurally and functionally, degeneration of retinal epithelial cells in age-related macular degeneration, and thus are expected to be widely used in the medical field.
Inventors:
LEE JUNWON (KR)
BYEON SUK HO (KR)
BYEON SUK HO (KR)
Application Number:
PCT/KR2022/006706
Publication Date:
November 17, 2022
Filing Date:
May 11, 2022
Export Citation:
Assignee:
UNIV YONSEI IACF (KR)
International Classes:
A61K31/455; A23L33/10; A61K31/706; A61P27/02
Foreign References:
| KR20170120583A | 2017-10-31 | |||
| KR20180039658A | 2018-04-18 | |||
| KR20170058976A | 2017-05-29 |
Other References:
EBELING MARA C., POLANCO JORGE R., QU JUN, TU CHENGJIAN, MONTEZUMA SANDRA R., FERRINGTON DEBORAH A.: "Improving retinal mitochondrial function as a treatment for age-related macular degeneration", REDOX BIOLOGY, vol. 34, 1 July 2020 (2020-07-01), NL , pages 1 - 13, XP093004003, ISSN: 2213-2317, DOI: 10.1016/j.redox.2020.101552
SAINI JANMEET S.; CORNEO BARBARA; MILLER JUSTINE D.; KIEHL THOMAS R.; WANG QINGJIE; BOLES NATHAN C.; BLENKINSOP TIMOTHY A.; STERN : "Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration", CELL STEM CELL, vol. 20, no. 5, 4 May 2017 (2017-05-04), AMSTERDAM, NL , pages 1 - 20, XP085000091, ISSN: 1934-5909, DOI: 10.1016/j.stem.2016.12.015
SAINI JANMEET S.; CORNEO BARBARA; MILLER JUSTINE D.; KIEHL THOMAS R.; WANG QINGJIE; BOLES NATHAN C.; BLENKINSOP TIMOTHY A.; STERN : "Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration", CELL STEM CELL, vol. 20, no. 5, 4 May 2017 (2017-05-04), AMSTERDAM, NL , pages 1 - 20, XP085000091, ISSN: 1934-5909, DOI: 10.1016/j.stem.2016.12.015
Attorney, Agent or Firm:
PADO IP LAW PLLC (KR)
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