Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING LRIT2 INHIBITOR AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2019/221516
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating cancer, comprising an LRIT2 inhibitor as an active ingredient. The LRIT2 inhibitor according to the present invention can increase the activity of immune cells, and thus can be used as an immune enhancer. Also, the LRIT2 inhibitor according to the present invention can effectively prevent or treat cancer by enhancing the immunity of an individual.
Inventors:
YOON KYOUNG WAN (KR)
HOUH YOUN KYUNG (KR)
JEON BU-NAM (KR)
SOHN JINYOUNG (KR)
KIM YUN YEON (KR)
LEE SURO (KR)
CHUNG JOO-YEON (KR)
JEONG AREUM (KR)
HOUH YOUN KYUNG (KR)
JEON BU-NAM (KR)
SOHN JINYOUNG (KR)
KIM YUN YEON (KR)
LEE SURO (KR)
CHUNG JOO-YEON (KR)
JEONG AREUM (KR)
Application Number:
PCT/KR2019/005853
Publication Date:
November 21, 2019
Filing Date:
May 15, 2019
Export Citation:
Assignee:
GENOME & COMPANY (KR)
International Classes:
C07K14/705; A61K38/00; A61P31/00; A61P35/00; C07K16/28
Domestic Patent References:
| WO2017211947A1 | 2017-12-14 |
Foreign References:
| US20170095531A1 | 2017-04-06 | |||
| US20150050647A1 | 2015-02-19 |
Other References:
HOUSTON, SAMUEL K.: "Regional and Temporal Differences in Gene Expression of LH BETA T AG Retinoblastoma Tumors", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol. 52, no. 8, 1 July 2011 (2011-07-01), pages 5359 - 5368, XP055653436, DOI: 10.1167/iovs.10-6321
UENO, AKIKO ET AL: "Lrit1, a retinal transmembrane protein, regulates selective synapse formation in cone photoreceptor cells and visual acuity", CELL REPORTS, vol. 22, no. 13, 27 March 2018 (2018-03-27), pages 3548 - 3561, XP055653448, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2018.03.007
UENO, AKIKO ET AL: "Lrit1, a retinal transmembrane protein, regulates selective synapse formation in cone photoreceptor cells and visual acuity", CELL REPORTS, vol. 22, no. 13, 27 March 2018 (2018-03-27), pages 3548 - 3561, XP055653448, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2018.03.007
Attorney, Agent or Firm:
FIRSTLAW P.C. (KR)
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