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Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING AS ACTIVE INGREDIENT MESENCHYMAL STEM CELLS WITH INCREASED PRODUCTION OF INTERLEUKIN 10 BY LACTOBACILLUS SAKEI CVL-001
Document Type and Number:
WIPO Patent Application WO/2023/224426
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating inflammatory diseases, comprising, as an active ingredient, mesenchymal stem cells with increased production of interleukin 10 by Lactobacillus sakei) CVL-001. Mesenchymal stem cells treated with the strain were confirmed to exhibit suppressed T cell proliferation and increased production of interleukin-10 (IL-10), and thus, the pharmaceutical composition can be effectively used as a composition for preventing, treating or ameliorating inflammatory diseases.

Inventors:
KIM HYUNG-SIK (KR)
KANG MIN-JUNG (KR)
PARK JONG-HWAN (KR)
Application Number:
PCT/KR2023/006828
Publication Date:
November 23, 2023
Filing Date:
May 19, 2023
Export Citation:
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Assignee:
NAT UNIV PUSAN IND UNIV COOP FOUND (KR)
UNIV NAT CHONNAM IND FOUND (KR)
International Classes:
A61K35/28; A23L33/10; A61K8/98; A61K35/747; A61P29/00; A61Q19/00
Foreign References:
KR20210148625A2021-12-08
KR20210112172A2021-09-14
KR20210031301A2021-03-19
KR102325947B12021-11-15
KR20140089805A2014-07-16
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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