PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OVERACTIVE BLADDER

WIPO Patent Application WO/2023/113114

A1

The present invention relates to: a novel quinazoline-based compound for activating BKCa channels; and a use thereof for preventing or treating an overactive bladder. The compound of the present invention can effectively activate BKCa channels, and thus can be used for preventing or treating an overactive bladder caused by the inactivation or an activity decrease of BKCa channels.

WO/2012/171903	NOVEL 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO[4,3-C]ISOQUINOLINE COMPOUNDS
JP2023048144	ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF
WO/2009/104155	2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES

PARK CHUL SEUNG (KR)
AHN JIN HEE (KR)
JO HEE JI (KR)
BAE EUN JUNG (KR)

PCT/KR2022/006678

June 22, 2023

May 10, 2022

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GWANGJU INST SCIENCE & TECH (KR)

C07D495/04; A61K31/519; A61P13/10

US20200222416A1	2020-07-16
US20150284387A1	2015-10-08
US20090175805A1	2009-07-09

LIM DONG HOON, MOON HYOUNG YOON, RHO JOON, KIM CHEOL SUNG: "Isolation of Methicillin-Resistant Staphylococcus aureus from the Urinary Tract: Clinical Characteristics and Antimicrobial Resistance ", KOREAN JOURNAL OF UROGENITAL TRACT INFECTION INFLAMMATION, vol. 3, no. 2, 1 October 2008 (2008-10-01), pages 208 - 214, XP093072601
KANT SASHI, ASTHANA SHAILENDRA, MISSIAKAS DOMINIQUE, PANCHOLI VIJAY: "A novel STK1-targeted small-molecule as an “antibiotic resistance breaker” against multidrug-resistant Staphylococcus aureus", SCIENTIFIC REPORTS, vol. 7, no. 1, XP093072602, DOI: 10.1038/s41598-017-05314-z

LEECHAE INTELLECTUAL PROPERTY (KR)

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