Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING SEQUELAE STAGE FACIAL NERVE PARALYSIS, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/051845
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for preventing and treating sequelae stage facial nerve paralysis. The pharmaceutical composition is selected from one among or a combination of mouse nerve growth factor, monosialoganglioside (GM1), cerebroside carnosine, mecobalamine, and cobamamide, a B-complex vitamin, butylphthalide, cinepazide maleate, edaravone, edaravone and dexborneol, citicoline, citicoline sodium,a ganglioside, oxiracetam, a brain protein, piracetam, a nerve growth factor, citicoline, neurotropin, oryzanol, vitamin B1, vitamin B6, vitamin B12, vitamin C, vitamin E, a compound brain peptide ganglioside, aniracetam, nervonic acid, or a nerve repairing cell protein extract or a nerve repairing protein composition having a repairing effect. The pharmaceutical of the present invention may be used in combination with a radio frequency operation or rehabilitative training.
Inventors:
CHEN LIN (CN)
WANG YU (CN)
GAO WENYONG (CN)
LI JIANJUN (CN)
WANG YU (CN)
GAO WENYONG (CN)
LI JIANJUN (CN)
Application Number:
PCT/CN2023/117897
Publication Date:
March 14, 2024
Filing Date:
September 09, 2023
Export Citation:
Assignee:
BEIJING DARWIN BIOTECH CO LTD (CN)
International Classes:
A61K31/714; A61K9/08; A61K31/365; A61K31/573; A61K31/7032; A61K38/18; A61P21/00; A61P25/02
Foreign References:
| CN102988403A | 2013-03-27 | |||
| CN106265678A | 2017-01-04 | |||
| CN113082043A | 2021-07-09 |
Other References:
MIAORUI LI: "Observation of Murine Nerve Growth Factor Combined with Methylcobalamin in Treatment of Idiopathic Facial Nerve Palsy", HEILONGJIANG JOURNAL OF TRADITIONAL CHINESE MEDICINE, 15 October 2019 (2019-10-15), pages 21 - 22, XP093148329
李延龙等 (LI, YANLONG ET AL.): "注射用鼠神经生长因子联合腺苷钴胺在面神经炎治疗中的临床观察 (Non-official translation: Clinical Observation of Murine Nerve Growth Factor Combined with Adenosylcobalamin for Injection in the Treatment of Facial Neuritis)", 医学信息 (JOURNAL OF MEDICAL INFORMATION), vol. 27, no. 8, 31 August 2014 (2014-08-31)
YUAN-HUI DU, ZENG QIANG; LIU LI; CHEN GUI-QUAN: "Research progress of drug for acupoint injection therapy treating peripheral facial paralysis", CHINA MODERN MEDICINE, vol. 24, no. 3, 28 January 2017 (2017-01-28), pages 20 - 23, XP093148333
李延龙等 (LI, YANLONG ET AL.): "注射用鼠神经生长因子联合腺苷钴胺在面神经炎治疗中的临床观察 (Non-official translation: Clinical Observation of Murine Nerve Growth Factor Combined with Adenosylcobalamin for Injection in the Treatment of Facial Neuritis)", 医学信息 (JOURNAL OF MEDICAL INFORMATION), vol. 27, no. 8, 31 August 2014 (2014-08-31)
YUAN-HUI DU, ZENG QIANG; LIU LI; CHEN GUI-QUAN: "Research progress of drug for acupoint injection therapy treating peripheral facial paralysis", CHINA MODERN MEDICINE, vol. 24, no. 3, 28 January 2017 (2017-01-28), pages 20 - 23, XP093148333
Attorney, Agent or Firm:
BEIJING ZHIDA TONGCHENG INTELLECTUAL PROPERTY AGENCY (CN)
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