PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF METABOLIC DISEASE COMPRISING LYSOPHOSPHOLIPID

Title:

PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF METABOLIC DISEASE COMPRISING LYSOPHOSPHOLIPID

Document Type and Number:

WIPO Patent Application WO/2023/068504

Kind Code:

A1

Abstract:

The present invention relates to a pharmaceutical composition for the prevention or treatment of a metabolic disease, comprising lysophospholipid. The pharmaceutical composition of the present invention promotes the PKA signaling pathway and upregulates lipolysis and mitochondrial oxidative metabolism, and thus can prevent or treat a metabolic disease such as obesity or diabetes.

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Inventors:

LEE YUN HEE (KR)
CHO YOON KEUN (KR)
IM HYEON YEONG (KR)
LEE SU MIN (KR)

Application Number:

PCT/KR2022/011626

Publication Date:

April 27, 2023

Filing Date:

August 05, 2022

Export Citation:

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Assignee:

SEOUL NAT UNIV R&DB FOUNDATION (KR)

International Classes:

A61K31/685; A23L33/10; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12

Foreign References:

KR20080019050A	2008-02-29
KR20120061016A	2012-06-12
KR20130099754A	2013-09-06
US6846801B1	2005-01-25

Other References:

SOGA, T. OHISHI, T. MATSUI, T. SAITO, T. MATSUMOTO, M. TAKASAKI, J. MATSUMOTO, S.-I. KAMOHARA, M. HIYAMA, H. YOS: "Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 326, no. 4, 28 January 2005 (2005-01-28), Amsterdam NL , pages 744 - 751, XP004682876, ISSN: 0006-291X, DOI: 10.1016/j.bbrc.2004.11.120

Attorney, Agent or Firm:

LEECHAE INTELLECTUAL PROPERTY (KR)

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