Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF MUSCLE DISEASE, COMPRISING MESENCHYMAL STEM CELL OR XCL1
Document Type and Number:
WIPO Patent Application WO/2017/142367
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating a muscle disease, the composition comprising mesenchymal stem cells, or an XCL1 protein or a derivative thereof, and a method for screening a muscle disease-treating agent. Effective in inhibiting the death of muscle cells or myoblasts, the mesenchymal stem cells or the XCL1 protein of the present invention can be usefully used for preventing or treating muscle diseases, and an inhibitory agent against cell death, containing an XCL1 protein can be used for cell death studies.
Inventors:
CHANG JONG WOOK (KR)
NA DUK LYUL (KR)
LEE JI EUN (KR)
KWON SOO JIN (KR)
NA DUK LYUL (KR)
LEE JI EUN (KR)
KWON SOO JIN (KR)
Application Number:
PCT/KR2017/001807
Publication Date:
August 24, 2017
Filing Date:
February 17, 2017
Export Citation:
Assignee:
SAMSUNG LIFE PUBLIC WELFARE FOUNDATION (KR)
International Classes:
A61K35/28; A01K67/027; A61K35/51; A61K38/17; C12N15/85; G01N33/50
Foreign References:
| KR20140070794A | 2014-06-11 | |||
| US20100310562A1 | 2010-12-09 | |||
| KR20100007241A | 2010-01-22 | |||
| KR20150015076A | 2015-02-10 | |||
| KR20070113087A | 2007-11-28 |
Other References:
KWON, S.: "Anti-apoptotic Effects of Human Wharton's Jelly-derived Mesenchymal Stem Cells on Skeletal Muscle Cells Mediated via Secretion of XCL1", MOL. THER., vol. 24, no. 9, 19 July 2016 (2016-07-19), pages 1550 - 1560, XP055601423
Attorney, Agent or Firm:
KIM, Soon Woong (KR)
Download PDF: