Title:
PHARMACEUTICAL COMPOSITION FOR TREATING BRAIN DISEASE, NEURONAL MIGRATION PROMOTER, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/058077
Kind Code:
A1
Abstract:
Provided is a technology that can promote neuronal migration. This pharmaceutical composition for treating brain disease includes a neuraminidase inhibiting substance. This neuronal migration promoter includes a neuraminidase inhibiting substance. This method for promoting neuronal migration includes a step for bringing a neuraminidase inhibiting substance into contact with neurons.
Inventors:
SAWAMOTO KAZUNOBU (JP)
MATSUMOTO MAMI (JP)
MATSUMOTO MAMI (JP)
Application Number:
PCT/JP2023/032912
Publication Date:
March 21, 2024
Filing Date:
September 08, 2023
Export Citation:
Assignee:
UNIV NAGOYA CITY PUBLIC UNIV CORP (JP)
International Classes:
A61K45/00; A61K31/351; A61P25/28; A61P43/00
Foreign References:
| JPH11310602A | 1999-11-09 |
Other References:
ERDIL ESRA; VURAL EZGI; KOYTAK PINAR KAHRAMAN; TUNCER EMINE NEŞE: "Successful treatment of influenza B associated acute necrotizing encephalopathy in an adult using combination of high dose oseltamivir–IVIG–pulse metylprednisolone", ACTA NEUROLOGICA BELGICA, ACTA MEDICA BELGICA, BE, vol. 121, no. 6, 9 August 2020 (2020-08-09), BE , pages 1863 - 1865, XP037616886, ISSN: 0300-9009, DOI: 10.1007/s13760-020-01462-8
ANONYMOUS: "Treatment strategies for influenza encephalopathy.", JAPAN AGENCY FOR MEDICAL RESEARCH AND DEVELOPMENT RESEARCH FUND, 1 February 2018 (2018-02-01), XP093146501, Retrieved from the Internet [retrieved on 20240328]
KOMORI YASUHIRO, UCHIDA NAOHIRO, SOEJIMA NAOKO, FUJITA YASUHIRO, MATSUMOTO HIROYUKI: "Successful Outcome in an Adult Patient with Influenza-associated Hemorrhagic Shock and Encephalopathy Syndrome", INTERNAL MEDICINE., JAPANESE SOCIETY OF INTERNAL MEDICINE, TOKYO., JP, vol. 59, no. 18, 15 September 2020 (2020-09-15), JP , pages 2321 - 2326, XP093146502, ISSN: 0918-2918, DOI: 10.2169/internalmedicine.4312-19
HA, Thi Kim Quy. Molecular networking-based chemical profiling and anti-influenza viral and neuroprotective effects of Elaeocarpus hygrophilus Kurz. Chemical Papers. 2021, vol. 75, pp. 5323-5337
LEAH K O'SHEA, SAMAR ABDULKHALEK, STEPHANIE ALLISON, RONALD J NEUFELD, MYRON R SZEWCZUK: "Therapeutic targeting of Neu1 sialidase with oseltamivir phosphate (Tamiflu®) disables cancer cell survival in human pancreatic cancer with acquired chemoresistance", ONCOTARGETS AND THERAPY, vol. 7, 1 January 2014 (2014-01-01), pages 117 - 134, XP055452856, DOI: 10.2147/OTT.S55344
ANONYMOUS: "Treatment strategies for influenza encephalopathy.", JAPAN AGENCY FOR MEDICAL RESEARCH AND DEVELOPMENT RESEARCH FUND, 1 February 2018 (2018-02-01), XP093146501, Retrieved from the Internet
KOMORI YASUHIRO, UCHIDA NAOHIRO, SOEJIMA NAOKO, FUJITA YASUHIRO, MATSUMOTO HIROYUKI: "Successful Outcome in an Adult Patient with Influenza-associated Hemorrhagic Shock and Encephalopathy Syndrome", INTERNAL MEDICINE., JAPANESE SOCIETY OF INTERNAL MEDICINE, TOKYO., JP, vol. 59, no. 18, 15 September 2020 (2020-09-15), JP , pages 2321 - 2326, XP093146502, ISSN: 0918-2918, DOI: 10.2169/internalmedicine.4312-19
HA, Thi Kim Quy. Molecular networking-based chemical profiling and anti-influenza viral and neuroprotective effects of Elaeocarpus hygrophilus Kurz. Chemical Papers. 2021, vol. 75, pp. 5323-5337
LEAH K O'SHEA, SAMAR ABDULKHALEK, STEPHANIE ALLISON, RONALD J NEUFELD, MYRON R SZEWCZUK: "Therapeutic targeting of Neu1 sialidase with oseltamivir phosphate (Tamiflu®) disables cancer cell survival in human pancreatic cancer with acquired chemoresistance", ONCOTARGETS AND THERAPY, vol. 7, 1 January 2014 (2014-01-01), pages 117 - 134, XP055452856, DOI: 10.2147/OTT.S55344
Attorney, Agent or Firm:
NOMURA Kazuhiro (JP)
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