Title:
PHARMACEUTICAL COMPOSITION FOR TREATING CANCER
Document Type and Number:
WIPO Patent Application WO/2023/132333
Kind Code:
A1
Abstract:
A pharmaceutical composition for treating cancer that contains a substance binding to laeverin; a method for identifying cancer recurrence and/or metastasis; a method for identifying a substance that impairs cancer cells expressing laeverin; a method for identifying a factor that affects cancer recurrence and/or metastasis; and use of laeverin as a cancer stem cell biomarker.
Inventors:
FUJIWARA HIROSHI (JP)
Application Number:
PCT/JP2023/000019
Publication Date:
July 13, 2023
Filing Date:
January 04, 2023
Export Citation:
Assignee:
FUJIWARA HIROSHI (JP)
International Classes:
A61K45/00; A61K39/395; A61K47/68; A61P35/00; A61P35/02; A61P35/04; C07K14/47; C07K16/28; C07K16/40; C12Q1/02
Foreign References:
| JP2019158613A | 2019-09-19 |
Other References:
HORIE A., FUJIWARA H., SATO Y., SUGINAMI K., MATSUMOTO H., MARUYAMA M., KONISHI I., HATTORI A.: "Laeverin/aminopeptidase Q induces trophoblast invasion during human early placentation", HUMAN REPRODUCTION, OXFORD JOURNALS, GB, vol. 27, no. 5, 1 May 2012 (2012-05-01), GB , pages 1267 - 1276, XP093077527, ISSN: 0268-1161, DOI: 10.1093/humrep/des068
FENG XUAN, WEI ZHI, ZHANG SAI, DU YAN, ZHAO HONGBO: "A Review on the Pathogenesis and Clinical Management of Placental Site Trophoblastic Tumors", FRONTIERS IN ONCOLOGY, vol. 9, 28 November 2019 (2019-11-28), pages 937, XP093077530, DOI: 10.3389/fonc.2019.00937
SONG GUO-QING, ZHAO YI: "Kisspeptin-10 inhibits the migration of breast cancer cells by regulating epithelial-mesenchymal transition", ONCOLOGY REPORTS, SPANDIDOS PUBL., vol. 33, no. 2, 1 February 2015 (2015-02-01), pages 669 - 674, XP093077531, ISSN: 1021-335X, DOI: 10.3892/or.2014.3619
FENG XUAN, WEI ZHI, ZHANG SAI, DU YAN, ZHAO HONGBO: "A Review on the Pathogenesis and Clinical Management of Placental Site Trophoblastic Tumors", FRONTIERS IN ONCOLOGY, vol. 9, 28 November 2019 (2019-11-28), pages 937, XP093077530, DOI: 10.3389/fonc.2019.00937
SONG GUO-QING, ZHAO YI: "Kisspeptin-10 inhibits the migration of breast cancer cells by regulating epithelial-mesenchymal transition", ONCOLOGY REPORTS, SPANDIDOS PUBL., vol. 33, no. 2, 1 February 2015 (2015-02-01), pages 669 - 674, XP093077531, ISSN: 1021-335X, DOI: 10.3892/or.2014.3619
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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