Title:
PHARMACEUTICAL PRODUCT AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/148279
Kind Code:
A1
Abstract:
A pharmaceutical product, comprising an antigen-binding protein targeting GITR and an immune checkpoint inhibitor, wherein the antigen-binding protein comprises at least one CDR in the VH having an amino acid sequence as shown in SEQ ID NO: 23, and comprises at least one CDR in the VL having an amino acid sequence as shown in SEQ ID NO: 24. Also provided is a use of the pharmaceutical product in the treatment of cancer.
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Inventors:
ZHANG XIN (CN)
DING JIAN (CN)
MA HUI (CN)
PAN XIAOLONG (CN)
FU SHILONG (CN)
ZHOU LIYAO (CN)
YUAN YANGYANG (CN)
MA SHULI (CN)
ZHAO MENG (CN)
SHI ERXIA (CN)
DING JIAN (CN)
MA HUI (CN)
PAN XIAOLONG (CN)
FU SHILONG (CN)
ZHOU LIYAO (CN)
YUAN YANGYANG (CN)
MA SHULI (CN)
ZHAO MENG (CN)
SHI ERXIA (CN)
Application Number:
PCT/CN2021/142299
Publication Date:
July 14, 2022
Filing Date:
December 29, 2021
Export Citation:
Assignee:
DINGFU BIOTARGET CO LTD (CN)
International Classes:
C07K16/28; A61K39/00; A61K39/395
Domestic Patent References:
| WO2015031667A2 | 2015-03-05 |
Foreign References:
| CN105492463A | 2016-04-13 | |||
| US20170260282A1 | 2017-09-14 | |||
| US20150353637A1 | 2015-12-10 | |||
| US20170355774A1 | 2017-12-14 | |||
| CA2772613A1 | 2011-03-10 | |||
| US20190364861A1 | 2019-12-05 |
Attorney, Agent or Firm:
SHANGHAI DIANSHI PARTNERS, P.C. (CN)
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