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Title:
PHARMACEUTICAL USE OF COMPLEX OF ARB METABOLITE AND NEP INHIBITOR IN PREVENTION AND/OR TREATMENT OF NEPHROPATHY
Document Type and Number:
WIPO Patent Application WO/2022/111493
Kind Code:
A1
Abstract:
A use of a complex of an ARB metabolite and an NEP inhibitor in the preparation of drugs for the prevention and/or treatment of nephropathy.

Inventors:
SUN JINGCHAO (CN)
XIAO YING (CN)
JING XIAOLONG (CN)
WANG RUHUAN (CN)
HU XUEFENG (CN)
Application Number:
PCT/CN2021/132617
Publication Date:
June 02, 2022
Filing Date:
November 24, 2021
Export Citation:
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Assignee:
SHENZHEN SALUBRIS PHARM CO LTD (CN)
International Classes:
A61K31/41; A61K31/216; A61P13/12; C07C233/47; C07D231/12; C07D403/10
Domestic Patent References:
WO2017125031A12017-07-27
Foreign References:
CN106466481A2017-03-01
CN105367438A2016-03-02
CN105461587A2016-04-06
CN106146472A2016-11-23
Other References:
JUDGE P., HAYNES R., LANDRAY M. J., BAIGENT C.: "Neprilysin inhibition in chronic kidney disease", NEPHROLOGY DIALYSIS TRANSPLANTATION, vol. 30, no. 5, 1 May 2015 (2015-05-01), GB , pages 738 - 743, XP055934317, ISSN: 0931-0509, DOI: 10.1093/ndt/gfu269
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