PHOSPHONATE NUCLEOTIDE DERIVATIVES - MISTUBISHI CHEMICAL CORP

Title:

PHOSPHONATE NUCLEOTIDE DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/1997/000262

Kind Code:

A1

Abstract:

A compound represented by general formula (I) and having an antiviral activity, wherein R1 represents hydrogen, C1-6 alkyl or C7-10 aralkyl; R2 represents C1-6 alkyl, C7-10 aralkyl or phenyl; R3 and R4 independently represent each hydrogen, C1-6 alkyl, acyloxymethyl, acylthioethyl or ethyl substituted by at least one halogen atom; R5 represents hydrogen, C1-4 alkyl, C1-4 hydroxyalkyl or C1-4 alkyl substituted by at least one halogen atom; and X represents carbon or nitrogen.

Inventors:

UBASAWA MASARU (JP)
TAKASHIMA HIDEAKI (JP)
SEKIYA KOUICHI (JP)
INOUE NAOKO (JP)
YUASA SATOSHI (JP)
KAMIYA NAOHIRO (JP)

Application Number:

PCT/JP1996/001631

Publication Date:

January 03, 1997

Filing Date:

June 14, 1996

Export Citation:

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Assignee:

MISTUBISHI CHEMICAL CORP (JP)
UBASAWA MASARU (JP)
TAKASHIMA HIDEAKI (JP)
SEKIYA KOUICHI (JP)
INOUE NAOKO (JP)
YUASA SATOSHI (JP)
KAMIYA NAOHIRO (JP)

International Classes:

C07F9/6561; (IPC1-7): C07F9/6561; A61K31/675

Domestic Patent References:

WO1994003467A2

1994-02-17

Foreign References:

JPH0770159A

1995-03-14

Other References: