Title:
PHOTOLABILE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2010/151879
Kind Code:
A9
Abstract:
The present invention describes Photolabile Compounds methods for use of the compounds. The Photolabile Compounds have a photoreleasable ligand, which can be biologically active, and which is photoreleased from the compound upon exposure to light. In some embodiments, the Photolabile Compounds comprise a light antenna, such as a labeling molecule or an active derivative thereof. In one embodiment, the light is visible light, which is not detrimental to the viability of biological samples, such as cells and tissues, in which the released organic molecule is bioactive and can have a therapeutic effect. In another embodiment, the photoreleasable ligand can be a labeling molecule, such as a fluorescent molecule.
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Inventors:
YUSTE RAFAEL (US)
ETCHENIOUE ROBERTO (AR)
BARALDO LUIS (AR)
ETCHENIOUE ROBERTO (AR)
BARALDO LUIS (AR)
Application Number:
PCT/US2010/040220
Publication Date:
March 24, 2011
Filing Date:
June 28, 2010
Export Citation:
Assignee:
UNIV COLUMBIA (US)
UNIV BUENOS AIRES (AR)
YUSTE RAFAEL (US)
ETCHENIOUE ROBERTO (AR)
BARALDO LUIS (AR)
UNIV BUENOS AIRES (AR)
YUSTE RAFAEL (US)
ETCHENIOUE ROBERTO (AR)
BARALDO LUIS (AR)
International Classes:
C07F1/00
Attorney, Agent or Firm:
LOVE, Jane, M. et al. (399 Park AvenueNew York, NY, US)
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