Title:
PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/008122
Kind Code:
A1
Abstract:
The present invention belongs to the field of chemical pharmaceuticals, and provided are a PI3K inhibitor, a preparation method therefor, and a use thereof. The PI3K inhibitor of the present invention is a compound as represented by formula I, or a salt thereof, a stereoisomer thereof, a solvate thereof, a hydrate thereof, or a prodrug thereof. The prepared compound can be used for preparing a PI3K selective inhibitor and for preparing a drug for preventing and/or treating a disease related to PI3K, such as a drug for preventing and/or treating cancer. The present invention provides a new choice for clinically treating cancer, and the present invention has good application prospects.
Inventors:
FAN LEI (CN)
YU HUA (CN)
WANG FEI (CN)
AI CHAOWU (CN)
XU KEXIN (CN)
LIU XINGTAI (CN)
DU JING (CN)
PENG YING (CN)
LUO TONGCHUAN (CN)
TAN BIN (CN)
WANG WENZHONG (CN)
YAN DEJUN (CN)
WANG XUZHAO (CN)
LI LIANG (CN)
XIAO DAIBIAO (CN)
LIU CHENGCHENG (CN)
LUO YAO (CN)
LI XINGHAI (CN)
CHEN YUANWEI (CN)
YU HUA (CN)
WANG FEI (CN)
AI CHAOWU (CN)
XU KEXIN (CN)
LIU XINGTAI (CN)
DU JING (CN)
PENG YING (CN)
LUO TONGCHUAN (CN)
TAN BIN (CN)
WANG WENZHONG (CN)
YAN DEJUN (CN)
WANG XUZHAO (CN)
LI LIANG (CN)
XIAO DAIBIAO (CN)
LIU CHENGCHENG (CN)
LUO YAO (CN)
LI XINGHAI (CN)
CHEN YUANWEI (CN)
Application Number:
PCT/CN2023/105915
Publication Date:
January 11, 2024
Filing Date:
July 05, 2023
Export Citation:
Assignee:
HINOVA PHARMACEUTICALS INC (CN)
International Classes:
C07D471/04; A61K31/352; A61K31/4433; A61P35/00; C07D405/04; C07D413/12; C07D487/04
Domestic Patent References:
| WO2023060262A1 | 2023-04-13 | |||
| WO2023078401A1 | 2023-05-11 | |||
| WO2023081209A1 | 2023-05-11 | |||
| WO2023104111A1 | 2023-06-15 | |||
| WO2022235574A1 | 2022-11-10 | |||
| WO2022251482A1 | 2022-12-01 | |||
| WO2021202964A1 | 2021-10-07 |
Foreign References:
| CN1688575A | 2005-10-26 | |||
| CN107001317A | 2017-08-01 |
Attorney, Agent or Firm:
GAOYUNG INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) CHENGDU (CN)
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