Title:
PICOLINAMIDE PARP INHIBITOR, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/138541
Kind Code:
A1
Abstract:
Disclosed are a picolinamide PARP inhibitor, and a preparation method therefor and the medical use thereof. Specifically, the present invention relates to a new compound as represented by general formula (1) and/or a pharmaceutically acceptable salt thereof, and a composition containing the compound as represented by general formula (1) and/or a pharmaceutically acceptable salt thereof, and a preparation method therefor and the use thereof as a PARP inhibitor in the preparation of an anti-tumor drug.
Inventors:
XIE YULI (CN)
LV YONGCONG (CN)
WU YINGMING (CN)
QIAN LIHUI (CN)
LV YONGCONG (CN)
WU YINGMING (CN)
QIAN LIHUI (CN)
Application Number:
PCT/CN2023/072425
Publication Date:
July 27, 2023
Filing Date:
January 16, 2023
Export Citation:
Assignee:
WIGEN BIOMEDICINE TECH SHANGHAI CO LTD (CN)
International Classes:
C07D401/12; A61K31/496; A61K31/498; A61K31/4985; A61P3/10; A61P9/10; A61P29/00; A61P35/00; C07D471/04
Domestic Patent References:
| WO2022222921A1 | 2022-10-27 | |||
| WO2022222966A1 | 2022-10-27 | |||
| WO2022222995A1 | 2022-10-27 | |||
| WO2022225934A1 | 2022-10-27 | |||
| WO2022228387A1 | 2022-11-03 | |||
| WO2022235585A1 | 2022-11-10 | |||
| WO2021260092A1 | 2021-12-30 | |||
| WO2021013735A1 | 2021-01-28 | |||
| WO2009053373A1 | 2009-04-30 |
Foreign References:
| CN115232154A | 2022-10-25 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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