Title:
PINITOL AND DERIVATIVES THEREOF FOR THE TREATMENT OF METABOLIC DISORDERS
Document Type and Number:
WIPO Patent Application WO1996029063
Kind Code:
A3
Abstract:
Pinitol and derivatives and metabolites thereof are useful in nutritional and medicinal compositions for treating conditions associated with insulin resistance, such as diabetes mellitus and its chronic complications; obesity; hyperlipidemias and dyslipidemias atherosclerosis; hypertension; cardiovascular disease; AIDS; cancer; wasting/cachexia; sepsis; trauma associated with burns, malnutrition, and stress; aging; lupus and other autoimmune diseases; endocrine disease; hyperuricemia, polycystic ovary syndrome and complications arising from athletic activity or inactivity.
Inventors:
OSTLUND RICHARD E
SHERMAN WILLIAM R
SHERMAN WILLIAM R
Application Number:
PCT/IB1996/000333
Publication Date:
October 31, 1996
Filing Date:
March 15, 1996
Export Citation:
Assignee:
UNIV WASHINGTON (US)
International Classes:
A61K31/075; A61P3/06; A61P3/08; C07C43/196; (IPC1-7): A61K31/045; A61K35/78
Other References:
S.S. HANDA ET AL.: "Hypoglycaemic plants. A review", FITOTERAPIA, vol. 60, no. 3, 1989, pages 195 - 224, XP000576828
C.R. NARANAYAN ET AL.: "Pinitol-a new anti-diabetic compound from the leaves of Bougainvillea spectabilis.", CURRENT SCIENCE, vol. 56, no. 3, 1987, pages 139 - 141, XP000577900
P. NORDIN: "Preferential leaching of pinitol from soybeans during imbibition.", PLANT PHYSIOL., vol. 76, no. 2, 1984, pages 313 - 315, XP000577873
D.V. PHILLIPS ET AL.: "Cyclitols in soybean.", AGRIC. FOOD CHEM., vol. 30, no. 1, 1982, pages 456 - 466, XP000577153
C.R. NARANAYAN ET AL.: "Pinitol-a new anti-diabetic compound from the leaves of Bougainvillea spectabilis.", CURRENT SCIENCE, vol. 56, no. 3, 1987, pages 139 - 141, XP000577900
P. NORDIN: "Preferential leaching of pinitol from soybeans during imbibition.", PLANT PHYSIOL., vol. 76, no. 2, 1984, pages 313 - 315, XP000577873
D.V. PHILLIPS ET AL.: "Cyclitols in soybean.", AGRIC. FOOD CHEM., vol. 30, no. 1, 1982, pages 456 - 466, XP000577153
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