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Title:
PIPERAZINE DERIVATIVES AS PARP1 INHIBITIORS
Document Type and Number:
WIPO Patent Application WO/2023/207284
Kind Code:
A1
Abstract:
Disclosed are piperazine derivatives and pharmaceutically acceptable salts thereof that inhibit the Poly (ADP-ribose) polymerase (PARP) family of enzymes. Also disclosed is the use of these compounds or pharmaceutically acceptable salts thereof in the treatment of diseases.

Inventors:
WANG TINGZHONG (CN)
SHEN ZHENHAI (CN)
TALBOT ERIC P A (GB)
BATEMAN JOSEPH M (GB)
RAHEMTULLA BENJAMIN F (GB)
MOROGLU MUSTAFA (GB)
LADDUWAHETTY TAMMY (GB)
Application Number:
PCT/CN2023/077273
Publication Date:
November 02, 2023
Filing Date:
February 20, 2023
Export Citation:
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Assignee:
NINGBO NEWBAY TECH DEVELOPMENT CO LTD (CN)
International Classes:
C07D471/04; A61K31/4353; A61K31/4375; A61K31/495; A61P35/00; C07D401/14; C07D403/14
Domestic Patent References:
WO2022222995A12022-10-27
WO2022228387A12022-11-03
WO2022223025A12022-10-27
WO2009053373A12009-04-30
WO2021260092A12021-12-30
Foreign References:
CN102341394A2012-02-01
CN114144413A2022-03-04
Attorney, Agent or Firm:
KING & WOOD MALLESONS (CN)
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