PIPERIDINE COMPOUND AND METHOD FOR PRODUCING SAME

Title:

PIPERIDINE COMPOUND AND METHOD FOR PRODUCING SAME

Document Type and Number:

WIPO Patent Application WO/2005/051912

Kind Code:

A1

Abstract:

Disclosed are a novel piperidine compound represented by the general formula [I] below which has an excellent tachykinin receptor antagonizing activity and pharmacologically acceptable salts thereof. [I] In the formula, ring A represents an optionally substituted benzene ring; ring B represents an optionally substituted benzene ring; R¹ represents an optionally substituted hydroxyl group, a thiol group having a substituent, a sulfonyl group having a substituent, or a group represented by the following formula [II]: wherein R¹¹ represents a carbonyl group having a substituent or a sulfonyl group having a substituent and R¹² represents a hydrogen atom or an optionally substituted alkyl group; R² represents a hydrogen atom or the like; Z represents an oxygen atom or a group represented by -N(R³)- wherein R³ represents an optionally substituted alkyl group or the like; R^4a represents an optionally substituted alkyl group; and R^4b represents an optionally substituted alkyl group.

Inventors:

TAKAHASHI MASAMI
MIYAKE TSUTOMU
YAMANAKA TAKESHI
ASAI HIDETOSHI
KONO RIKAKO

Application Number:

PCT/JP2004/017543

Publication Date:

June 09, 2005

Filing Date:

November 26, 2004

Export Citation:

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Assignee:

TANABE SEIYAKU CO (JP)
TAKAHASHI MASAMI
MIYAKE TSUTOMU
YAMANAKA TAKESHI
ASAI HIDETOSHI
KONO RIKAKO

International Classes:

C07D211/38; C07D211/46; C07D211/54; C07D211/56; C07D211/58; A61K31/451; A61P1/04; A61P7/02; A61P9/10; A61P9/12; A61P17/04; A61P17/06; A61P19/10; A61P25/00; A61P25/06; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/36; A61P27/02; A61P27/16; A61P29/00; A61P37/02; A61P37/08; A61P43/00; (IPC1-7): C07D211/46; C07D211/38; C07D211/54; C07D211/56

Domestic Patent References:

WO2003066589A1

2003-08-14

Foreign References:

JP2003511377A	2003-03-25
JPH07196649A	1995-08-01

Other References: