POLYAMINE DERIVATIVE MEDICINAL SALT AND PREPARATION METHOD AND USE

Title:

POLYAMINE DERIVATIVE MEDICINAL SALT AND PREPARATION METHOD AND USE

Document Type and Number:

WIPO Patent Application WO/2017/071629

Kind Code:

A1

Abstract:

The invention relates to a polyamine derivative medicinal salt and preparation method and use in preparation of a drug for treating pyemia. The novel compound has good antagonistic action on a plurality of pyemia-causing pathogen-related molecules such as bacterial lipopolysaccharide (endotoxin), bacterial genome DNA, peptidoglycan, teichoic acid, virus RNA, and zymosan, and can be used for preparation of a drug for treating pyemia.

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Inventors:

ZHENG YUE (CN)
DENG JUN (CN)
LIU QINGGUANG (CN)

Application Number:

PCT/CN2016/103693

Publication Date:

May 04, 2017

Filing Date:

October 28, 2016

Export Citation:

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Assignee:

CHONGQING ANTIXIN BIOTECHNOLOGY CO LTD (CN)

International Classes:

C07C235/34; A61P29/00; A61P31/00; C07C233/40

Foreign References:

CN102267922A

2011-12-07

Other References:

TRACHSEL, A. ET AL.: "Parameters Influencing the Release of Tertiary Alcohols from the Surface of 'Spherical' Dendrimers and 'Lincar' Stylomers by Neighbouring-Group-Assisted Hydrolysis of 2-Carbamoylbenzoates", CHEMISTRY-A EUROPEAN JOURNAL, vol. 15, no. 12, 9 March 2009 (2009-03-09), pages 2848 - 2860, XP055538966, ISSN: 1521-3765, DOI: 10.1002/chem.200801350
See also references of EP 3369725A4

Attorney, Agent or Firm:

CHONGQING ZHIHE PATENT AGENCY (CN)

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