Title:
POLYFUNCTIONAL BIOCOMPATIBLE HYDROGEL AND METHOD FOR THE PRODUCTION THEREOF
Document Type and Number:
WIPO Patent Application WO/2003/026711
Kind Code:
A1
Abstract:
The inventive polyfunctional biocompatible hydrogel comprises 1.3-15 mass % of acrylamide, 0-004-0.975 mass % of cross-linking agents- N,N'-methylen-bis-acrylamide, 0.004-5.1 mass % of N,N'-ethylen-bis-acrylamide, 0.002-0.45 mass % of poviargol and water up to 100 mass %. Said hydrogel is produced by sopolymerising acrylamide with the cross-linking agents in an aqueous medium in the presence of peroxide polymerisation initiator, the incubation of reaction mixture being carried out in two stages. The first stage is carried out at a temperature ranging from 20 to 90 °C during a time of 2 to 24 hours, the second stage being carried out at a temperature ranging from 107 to 130 °C during a time equal to or less than 2 hours.
Inventors:
LOPATIN VLADISLAV VICTOROVICH (RU)
Application Number:
PCT/RU2001/000392
Publication Date:
April 03, 2003
Filing Date:
September 28, 2001
Export Citation:
Assignee:
LOPATIN VLADISLAV VICTOROVICH (RU)
BIOPHARMA DEV LTD (GB)
BIOPHARMA DEV LTD (GB)
International Classes:
A61L27/16; A61L27/52; A61L27/54; A61P41/00; C08K5/00; C08K3/08; (IPC1-7): A61L27/16; A61L27/52
Domestic Patent References:
| WO1999010021A1 | 1999-03-04 |
Foreign References:
| RU2127095C1 | 1999-03-10 | |||
| RU2067873C1 | 1996-10-20 | |||
| EP0727232A2 | 1996-08-21 | |||
| US5941909A | 1999-08-24 |
Other References:
See also references of EP 1438976A4
Attorney, Agent or Firm:
Sadovnikova, Lyudmila Georgievna (32-50 Puschin, Moskovskaya obl. 0, RU)
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