POLYMER-COATED FERRITE MICROPARTICLES AND PRODUCTION METHOD FOR SAME

Title:

POLYMER-COATED FERRITE MICROPARTICLES AND PRODUCTION METHOD FOR SAME

Document Type and Number:

WIPO Patent Application WO/2011/052205

Kind Code:

A1

Abstract:

Disclosed are polymer-coated ferrite microparticles which exhibit suitable water dispersion properties and an excellent biomolecular immobilisation ability, and which can be controlled so as to have a uniform particle diameter. Further disclosed is a simple production method for the microparticles. In an aqueous solvent, a polyacrylic acid is chelated with ferrous ions, the resulting chelate complex is protected, and then an alkali is added. Subsequently, the reaction system is heated under pressurised conditions, causing the precipitation of ferrite microparticles and the coating of said microparticles to occur simultaneously. As a result, polymer-coated ferrite microparticles having a uniform particle diameter can be obtained in large quantities, in one step and with good repeatability. The disclosed polymer-coated ferrite microparticles exhibit suitable water dispersion properties and an excellent biomolecular immobilisation ability as a result of the carboxyl groups derived from the polyacrylic acid.

Inventors:

HANDA HIROSHI (JP)
HATAKEYAMA MAMORU (JP)
SAKAMOTO SATOSHI (JP)
KISHI HIROSHI (JP)

Application Number:

PCT/JP2010/006364

Publication Date:

May 05, 2011

Filing Date:

October 28, 2010

Export Citation:

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Assignee:

TOKYO INST TECH (JP)
HANDA HIROSHI (JP)
HATAKEYAMA MAMORU (JP)
SAKAMOTO SATOSHI (JP)
KISHI HIROSHI (JP)

International Classes:

C01G49/06; A61K47/02; A61K49/00; H01F1/34

Domestic Patent References:

WO2008081917A1

2008-07-10

Foreign References:

JP2005060221A	2005-03-10
JP2008280277A	2008-11-20
JP2007216134A	2007-08-30
JP2009114066A	2009-05-28

Other References: