Title:
POLYMERIZABLE BIOTIN DERIVATIVES, BIOTIN POLYMER, AND POLYMER RESPONSIVE TO AVIDIN STIMULATION
Document Type and Number:
WIPO Patent Application WO/2001/009141
Kind Code:
A1
Abstract:
Novel polymerizable biotin derivatives which are represented by general formula (I). A polyfunctional polymer can be synthesized therefrom. In formula (I), R?2¿ represents hydrogen or alkyl; R?3¿ and R?4¿ each represents hydrogen, alkyl, or aryl; T represents oxygen or =NH; W represents a single bond, carbonyl, thiocarbonyl, or C¿1-5? alkylene; U represents a single bond or -NH-; X represents a single bond, a C¿1-8? hydrocarbon bond, oxygen, or -NH-; Y represents a single bond, carbonyl, thiocarbonyl, -NH-, 1,2-dioxyethylene, or 1,2-diaminoethylene; Z represents a single bond, carbonyl, thiocarbonyl, C¿1-5? alkylene, oxygen, or -NH-; and V represents a single bond or C¿1-5? alkylene.
Inventors:
OHNISHI NORIYUKI (JP)
YOSHIDA MIKIKO (JP)
KATAOKA KAZUNORI (JP)
UENO KATSUHIKO (JP)
YOSHIDA MIKIKO (JP)
KATAOKA KAZUNORI (JP)
UENO KATSUHIKO (JP)
Application Number:
PCT/JP2000/005113
Publication Date:
February 08, 2001
Filing Date:
July 28, 2000
Export Citation:
Assignee:
AGENCY IND SCIENCE TECHN (JP)
JAPAN CHEMICAL INNOVATION INST (JP)
OHNISHI NORIYUKI (JP)
YOSHIDA MIKIKO (JP)
KATAOKA KAZUNORI (JP)
UENO KATSUHIKO (JP)
JAPAN CHEMICAL INNOVATION INST (JP)
OHNISHI NORIYUKI (JP)
YOSHIDA MIKIKO (JP)
KATAOKA KAZUNORI (JP)
UENO KATSUHIKO (JP)
International Classes:
C07D495/04; C08F20/38; C08F246/00; (IPC1-7): C07D495/04; C08F20/38; C08F20/54; C12N11/08
Domestic Patent References:
| WO1986001899A1 | 1986-03-27 | |||
| WO1995031730A1 | 1995-11-23 | |||
| WO1997000329A2 | 1997-01-03 | |||
| WO1996004402A1 | 1996-02-15 | |||
| WO1999064378A2 | 1999-12-16 |
Foreign References:
| EP0226470A2 | 1987-06-24 | |||
| EP0914835A2 | 1999-05-12 | |||
| JPH0296581A | 1990-04-09 | |||
| US5863748A | 1999-01-26 | |||
| EP0011777A1 | 1980-06-11 | |||
| EP0922715A2 | 1999-06-16 | |||
| JPH0949830A | 1997-02-18 |
Other References:
TARASOW T. ET AL.: "Characteristics of an RNA diels-alderase active site", J. AM. CHEM. SOC., vol. 121, no. 15, 1999, pages 3614 - 3617, XP002932606
NELSON P. ET AL.: "Convenient preparation of new C-5 biotinylated dUTP derivative", NUCLEOSIDES NUCLEOTIDES, vol. 5, no. 3, 1986, pages 233 - 241, XP002932607
See also references of EP 1201667A4
NELSON P. ET AL.: "Convenient preparation of new C-5 biotinylated dUTP derivative", NUCLEOSIDES NUCLEOTIDES, vol. 5, no. 3, 1986, pages 233 - 241, XP002932607
See also references of EP 1201667A4
Attorney, Agent or Firm:
Oguri, Shohei (28th Floor 12-32, Akasaka 1-chome Minato-ku Tokyo, JP)
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